Results 231 to 240 of about 74,506 (264)

PPARγ contributes to cardioprotection against heat stroke through ABCC5-dependent lipid metabolism. [PDF]

Redox Biol
Shen M, Zhao A, Hao G, Lei W, Li N, Deng C, Wang X, Chen Y, Zhang Z, Dong Y, Yang Y.   +10 more
europepmc   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 841-858, July 2026.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique, Muhammad Muzammil Nazir, Saima Muzammil, Iqra Farzeen, Shafaq Latif, Asma Ashraf, Jorddy Neves Cruz   +6 more
wiley   +1 more source

NEK2A regulates PLIN2 expression through a SERBP1 dependent pathway. [PDF]

iScience
Makiyama T, Aiuchi T, Mikajiri T, Obama T, Chatani M, Azetsu Y, Yamada A, Sasa K, Itabe H.   +8 more
europepmc   +1 more source

Soybean‐Derived Exosome‐Like Nanovesicles Regulate Lipid Metabolism via Mitochondrial Biogenesis and UCP1/PGC‐1α Mediated Thermogenesis

Food Frontiers, Volume 7, Issue 4, July 2026.
Soybean‐derived exosome‐like nanovesicles suppress lipid accumulation of adipocytes via UCP1/PGC‐1α mediated thermogenesis pathway and boosting mitochondrial function. ABSTRACT Obesity has become an important public health concern in modern society. Plant‐derived exosome‐like nanovesicles are emerging as candidates for obesity intervention.
Zhenzhu Zhu, Luyuan Ni, Mingwei Gao, Qian Yang, Changli Zhang, Qin Liu   +5 more
wiley   +1 more source

<i>Porphyromonas gingivalis</i> triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway. [PDF]

Mol Med Rep
Lin XJ, Yao M, Lin WY, Yuan Q, Zhou J, Xia WX, Dong YL, Zhang MM, Cui MW, Wu LH, Sunchuri D, Ullah Shahid MZ, Guo ZL.   +12 more
europepmc   +1 more source

Luteolin Glycoside From Dracocephalum moldavica L. Attenuates COPD by Modulating TLR4 Expression and Alveolar Cross‐Talk

Food Frontiers, Volume 7, Issue 4, July 2026.
Luteolin‐7‐O‐β‐d‐glucuronide mitigates CS‐induced COPD progression by promoting cytokine‐mediated functional cross‐talk between alveolar macrophages and epithelial cells. ABSTRACT Chronic obstructive pulmonary disease (COPD) is associated with inflammation of the airway and lung parenchyma with limited airflow due to continued exposure to harmful ...
Jianhu Jia, Tiantian Liu, Jiamin Huang, Na Zheng, Wei Wang, Song Wang, Wenjun Wang, Ghulam Jilany Khan, Jianhua Yang, Chenghui He, Fei Li, Hong Duan, Henggui Hu, Kefeng Zhai   +13 more
wiley   +1 more source

Performance of Seven-Gene Panel Testing for Risk Stratification of Thyroid Nodules with Indeterminate Cytology Results. [PDF]

Int J Mol Sci
Jochum AK, Renström F, Bischofberger-Baumann B, Demmer I, Schönegg R, Brändle M, Bilz S, Jochum W.   +7 more
europepmc   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

Structural optimization of drug molecules with incrementally trained language models. [PDF]

Nat Commun
Hörmann T, Mayer D, Lewandowski M, Hunklinger A, Wein T, Merk D.   +5 more
europepmc   +1 more source

Lessons From Astaxanthin Therapy to Combat Oral Premalignant and Malignant Lesions: A Narrative Review

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Oral cancer is one of the most common head and neck malignancies and remains associated with high morbidity, mortality, and treatment‐related toxicity. Despite advances in surgery, radiotherapy, and chemotherapy, there is still a need for safer adjunctive therapies with better therapeutic potential.
Reza Arefnezhad, Zhina Mohamadi, Shervin Shahianjahromi, Amirali Fallahian, Maryam Ashrafi, Armin Nikdehqan, Mitra Saeedi Valashani, Reza Nasiri, Fatemeh Zeinali, Hossein Fatemian, Niloofar Sefati, Fatemeh Rezaei‐Tazangi, Marziye Ranjbar Tavakoli   +12 more
wiley   +1 more source