Results 91 to 100 of about 43,347 (215)

The Role of PPAR-gamma C161T Polymorphism in Colorectal Cancer Susceptibility. [PDF]

In Vivo, 2022
Kurnaz-Gomleksiz O, Torun BC, Isbir T, Bulut T, Sokucu N, Yilmaz-Aydogan H, Canbay E.   +6 more
europepmc   +1 more source

Regulating Lipid Metabolism in Cancer: The Therapeutic Potential of Traditional Chinese Medicine

Phytotherapy Research, EarlyView.
By regulating the reprogramming of lipid metabolism in tumor cells, TCM provides a novel strategy for antitumor therapy with reduced toxicity and enhanced efficacy. ABSTRACT Lipid metabolic reprogramming is a key feature of tumor cells to adapt to the microenvironment and plays an important role in tumor growth, invasion, and metastasis.
Yufeng Gao, Huiming Huang, Xuejiao Wei, Xiaoxue Wang, Wanying Xie, Xinyu Qiu, Fei Wang, Zhuguo Wang, Ruoxin Zhang, Yilin Cai, Changhai Qu, Zhongdong Hu   +11 more
wiley   +1 more source

Saroglitazar for the treatment of hypertriglyceridemia in patients with type 2 diabetes: current evidence

Diabetes, Metabolic Syndrome and Obesity, 2015
Aravind Sosale,1 Banshi Saboo,2 Bhavana Sosale11Diacon Hospital, Bangalore, 2Dia Care (Diabetes Care and Hormone Clinic), Ahmedabad, IndiaAbstract: Diabetes mellitus (DM) is one of the most dreaded metabolic disorders in the world today.
Sosale A, Saboo B, Sosale B
doaj  

Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway

Drug Design, Development and Therapy, 2020
Shihao Xiang, 1,* Kan Chen, 2,* Ling Xu, 3 Ting Wang, 3 Chuanyong Guo 1, 2 1Medical College of Soochow University, Suzhou, 215006, People’s Republic of China; 2Department of Gastroenterology, Shanghai Tenth People’s Hospital, Tongji ...
Xiang S, Chen K, Xu L, Wang T, Guo C
doaj  

Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway. [PDF]

PLoS One, 2023
Badshah I, Qazi NG, Ali F, Minhas AM, Alvi AM, Kandeel M, Imran M, Hassan SSU, Bungau S.   +8 more
europepmc   +1 more source

Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation

Rheumatology &Autoimmunity, EarlyView.
The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang, Rongyuan Gao, Zhaohui Zheng   +2 more
wiley   +1 more source

In silico approach for the discovery of new PPARγ modulators among plant-derived polyphenols

Drug Design, Development and Therapy, 2015
José Antonio Encinar,1 Gregorio Fernández-Ballester,1 Vicente Galiano-Ibarra,2 Vicente Micol1,3 1Molecular and Cell Biology Institute, 2Physics and Computer Architecture Department, Miguel Hernández University, Elche, Spain; 3CIBER ...
Encinar JA, Fernández-Ballester G, Galiano-Ibarra V, Micol V   +3 more
doaj  

Hypoglycemic Activity of Curcuma mangga Val. Extract via Modulation of GLUT4 and PPAR-γ mRNA Expression in 3T3-L1 Adipocytes

Journal of Experimental Pharmacology, 2020
Dwiyati Pujimulyani,1 Wisnu Adi Yulianto,1 Astuti Setyowati,1 Seila Arumwardana,2 Hanna Sari Widya Kusuma,2 Ika Adhani Sholihah,2 Rizal Rizal,2,3 Wahyu Widowati,4 Ali Maruf5 1Faculty of Agroindustry, University of Mercu Buana Yogyakarta, Yogyakarta 55753,
Pujimulyani D, Yulianto WA, Setyowati A, Arumwardana S, Sari Widya Kusuma H, Adhani Sholihah I, Rizal R, Widowati W, Maruf A   +8 more
doaj  

Microplastics and the Endocrine–Metabolic Interface: Novel Diagnostic Tools Targeting Thyroid–Adipose Axis

Environmental Toxicology, EarlyView.
ABSTRACT Microplastics (MPs) have been identified as major environmental contaminants that can affect organisms directly and act as carriers of particles and chemical additives, thereby aggravating endocrine networks that coordinate metabolic homeostasis.
Sunday Amos Onikanni, Babasola Aiyeku, Marjorie Dardis Murucci, Temitope Aribigbola, Kenia Bispo, Oluwatosin Stella Olayinka, Rômulo Sperduto Dezonne, Sara Gemini Piperni, Paula Soares, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source