Results 31 to 40 of about 41,660 (152)

Emerging role of the peroxisome proliferator-activated receptor-gamma in hepatocellular carcinoma

open access: yesJournal of Hepatocellular Carcinoma, 2014
Hui-Tzu Hsu,1 Chin-Wen Chi1,21Department and Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 2Department of Medical Research, Taipei Veterans General Hospital, Taipei, TaiwanAbstract: Hepatocellular carcinoma
Hsu HT, Chi CW
doaj  

Soy milk and ginger (Sulehe) increase PPAR-γ expression in a rat model of insulin resistance

open access: yesСахарный диабет, 2018
Background: Diabetes mellitus type 2 is metabolic disease characterized by hyperglycemia due to a defect in insulin secretion resulting in insulin resistance. This disease leads to dysfunction of various organs including eyes, kidneys, and heart.
Wiwik Handayani   +3 more
doaj   +1 more source

Effects Of PPARγ2 Pro12Ala Variant On Adipocyte Phenotype Dependent Of DHA

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2019
Renhui Wan,* Zhengping Ding,* Sheng Xia, Longyi Zheng, Jin Lu Department of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai 200433, People’s Republic of China*These authors contributed equally to this ...
Wan R, Ding Z, Xia S, Zheng L, Lu J
doaj  

Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma

open access: yesFrontiers in Physiology, 2017
Gliomas cells are the site of numerous metabolic and thermodynamics abnormalities with an increasing entropy rate which is characteristic of irreversible processes driven by changes in Gibbs energy, heat production, intracellular acidity, membrane ...
Alexandre Vallée   +5 more
doaj   +1 more source

PPAR gamma, bioactive lipids, and cancer progression [PDF]

open access: yesFrontiers in Bioscience, 2012
In this article we review the evolution of cancer research involving PPARgamma, including mechanisms, target genes, and clinical applications. For the last thirteen years, the effects of PPARgamma activity on tumor biology have been studied intensely. Most of this research has focused upon the potential for employing agonists of this nuclear receptor ...
Gregory T, Robbins, Daotai, Nie
openaire   +2 more sources

Synergism in hyperhomocysteinemia and diabetes: role of PPAR gamma and tempol

open access: yesCardiovascular Diabetology, 2010
Background Hyperhomocysteinemia (HHcy) and hyperglycemia cause diabetic cardiomyopathy by inducing oxidative stress and attenuating peroxisome proliferator- activated receptor (PPAR) gamma. However, their synergistic contribution is not clear.
Mishra Paras K   +4 more
doaj   +1 more source

Synthesis and Biological Activity of Piperine Derivatives as Potential PPARγ Agonists

open access: yesDrug Design, Development and Therapy, 2020
Yanli Wang,1– 3 Yuan Yao,4,5 Jing Liu,2,6 Lili Wu,7 Tonghua Liu,7 Jian Cui,1 David Yue-Wei Lee2 1School of Pharmacy, Minzu University of China, Beijing 100081, People’s Republic of China; 2Bio-Organic and Natural Products Laboratory, McLean ...
Wang Y   +6 more
doaj  

Synthesis, activity, and docking study of phenylthiazole acids as potential agonists of PPARγ

open access: yesDrug Design, Development and Therapy, 2016
Liang Ma,1,* Taijin Wang,2,* Min Shi,1 Haoyu Ye2 1Department of Nephrology, Kidney Research Institute, 2State Key Laboratory of Biotherapy and Cancer Center/Collaborative Innovation Center of Biotherapy, West China Hospital, West China Medical School of
Ma L, Wang T, Shi M, Ye H
doaj  

Inhibition of Irvingia gabonensis seed extract (OB131) on adipogenesis as mediated via down regulation of the PPARgamma and Leptin genes and up-regulation of the adiponectin gene

open access: yesLipids in Health and Disease, 2008
Background Endeavors to manage obesity have been heavily reliant on controlling energy intake and expenditure equilibrium, but have failed to curtail the overweight and obesity epidemic. This dynamic equilibrium is more complex than originally postulated
Blum Kenneth   +2 more
doaj   +1 more source

In silico validation of microalgal metabolites against Diabetes mellitus

open access: yesСахарный диабет, 2017
Aim. Present study aimed to evaluate the efficiency of microalgal metabolites as ligands for anti-diabetic target proteins viz., glucokinase, fructose-1, 6-bisphosphatase, glycogen synthase kinase, cytochrome P450, multi drug resistant protein, and ...
Gurudeeban Selvaraj   +3 more
doaj   +1 more source

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