Results 11 to 20 of about 41,660 (152)
A Systematic Review of Clinical and Experimental Periodontitis Studies Demonstrating the Expression of PPAR-Gamma: A Meta-Analysis and Bioinformatics Approach [PDF]
BiomedicinesRaquel Scarel-Caminaga +2 more
exaly +2 more sources
Immunoregulatory actions of epithelial cell PPAR gamma at the colonic mucosa of mice with experimental inflammatory bowel disease. [PDF]
PLoS ONE, 2010 BACKGROUND: Peroxisome proliferator-activated receptors are nuclear receptors highly expressed in intestinal epithelial cells (IEC) and immune cells within the gut mucosa and are implicated in modulating inflammation and immune responses.
Saroj K Mohapatra +7 more
doaj +1 more source
PPAR gamma Agonists – Plant Compounds [PDF]
Journal of Stress Physiology & Biochemistry, 2023 The nuclear receptor peroxisome proliferator activated receptor-gamma (PPARg) controls adipocyte differentiation, as well as lipid metabolism and insulin sensitivity.
Anil Kumar Moola, Shobana G., C. Janani
doaj
Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons
Cardiovascular Diabetology, 2005 There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly designated PPAR alpha, PPAR gamma and PPAR beta/delta.
Tenenbaum Alexander +2 more
doaj +1 more source
PPAR Gamma and Hepatic Stellate Cells [PDF]
Comparative Hepatology, 2004 Activation of Hepatic stellate cells (HSC) in fibrogenesis involves distinct morphological and biochemical changes. This activation requires the coordinated changes in activity of several transcription factors. Peroxisome proliferator-activated receptor gamma (PPAR gamma) is one such factor whose activity is decreased in activated HSC.
Hazra, Saswati +3 more
openaire +2 more sources
Frontiers in Neuroscience, 2016 The molecular mechanisms underlying the pathophysiology of Alzheimer's disease (AD) are still not fully understood. In AD, Wnt/beta-catenin signaling has been shown to be downregulated while the peroxisome proliferator-activated receptor (PPAR) gamma ...
Alexandre VALLEE, Yves Lecarpentier
doaj +1 more source
Molecules, 2018 Type 2 diabetes (T2D) is a metabolic disorder where insulin-sensitive tissues show reduced sensitivity towards insulin and a decreased glucose uptake (GU), which leads to hyperglycaemia.
Lars Porskjær Christensen +1 more
doaj +1 more source
Peroxisome Proliferator-Activated Receptors and the Hallmarks of Cancer
Cells, 2022 Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors upon the binding of physiological or pharmacological ligands and heterodimerization with retinoic X receptors.
Nicole Wagner, Kay-Dietrich Wagner
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Frontiers in Physiology, 2014 Circadian clock mechanisms are far-from-equilibrium dissipative structures. Peroxisome proliferator-activated receptors (PPAR alpha, beta/delta and gamma) play a key role in metabolic regulatory processes, particularly in heart muscle.
Yves eLecarpentier +3 more
doaj +1 more source
Frontiers in Aging Neuroscience, 2010 Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear transcription factors that regulate peripheral lipid and glucose metabolism. Three subtypes make up the PPAR family (α, γ, β/δ), and synthetic ligands
Nektaria Nicolakakis, Edith Hamel
doaj +1 more source