The Role of PPAR Gamma in Systemic Sclerosis [PDF]
PPAR Research, 2015 Fibrosis is recognized as an important feature of many chronic diseases, such as systemic sclerosis (SSc), an autoimmune disease of unknown etiology, characterized by immune dysregulation and vascular injury, followed by progressive fibrosis affecting ...
Andréa Tavares Dantas +7 more
doaj +4 more sources
PPAR Gamma and Angiogenesis: Endothelial Cells Perspective [PDF]
Journal of Diabetes Research, 2016 We summarize the current knowledge concerning PPARγ function in angiogenesis. We discuss the mechanisms of action for PPARγ and its role in vasculature development and homeostasis, focusing on endothelial cells, endothelial progenitor cells, and bone ...
Jerzy Kotlinowski, Alicja Jozkowicz
doaj +3 more sources
PPAR-gamma Fun(gi) With Prostaglandin. [PDF]
Nucl Recept Signal, 2020 In our recent publication, we show for the first time that the fungal pathogen Cryptococcus neoformans is able to manipulate host cells by producing eicosanoids that mimic those found in the host. Using complementary in vivo zebrafish and in vitro macrophage cell culture models of Cryptococcus infection, we found that these eicosanoids manipulate host
Evans RJ, Johnston SA.
europepmc +5 more sources
Studies on the contribution of PPAR Gamma to tuberculosis physiopathology. [PDF]
Front Cell Infect Microbiol, 2023 IntroductionTuberculosis (TB) is a major health problem characterized by an immuno-endocrine imbalance: elevated plasma levels of cortisol and pro- and anti-inflammatory mediators, as well as reduced levels of dehydroepiandrosterone. The etiological agent, Mycobacterium tuberculosis (Mtb), is captured by pulmonary macrophages (Mf), whose activation is ...
Díaz A +9 more
europepmc +5 more sources
Alteration of PPAR-GAMMA (PPARG; PPARγ) and PTEN gene expression in acute myeloid leukemia patients and the promising anticancer effects of PPARγ stimulation using pioglitazone on AML cells. [PDF]
Mol Genet Genomic Med, 2021 Esmaeili S +4 more
europepmc +3 more sources
PPAR-gamma Signaling in Metabolic Homeostasis
Indonesian Biomedical Journal, 2016 INTRODUCTION: Peroxisome proliferator-activated receptor (PPAR)-γ, or also known as nuclear receptor subfamily 1 group C member 3 (NR1C3), is a PPAR which serves as master regulator of adipocytes differentiation, and plays an important role in lipid ...
Rina Triana +6 more
doaj +3 more sources
Retraction Note to: Coffee component hydroxyl hydroquinone (HHQ) as a putative ligand for PPAR gamma and implications in breast cancer. [PDF]
BMC Genomics, 2022 Shashni B +6 more
europepmc +3 more sources
The Effect of Soy Isoflavones on the PPAR alpha and PPAR gamma Pathways
, 2022 Orsolya Mezei
openalex +2 more sources
Renoprotective effect of dulaglutide in L-NAME-induced hypertensive nephropathy in rats: insight into the roles of PPAR-gamma and VEGF. [PDF]
Hypertens ResBastawy N +8 more
europepmc +3 more sources
Angiotensin II, PPAR-Gamma and atherosclerosis [PDF]
Frontiers in Bioscience, 2004 Atherosclerosis is a complex, chronic disease state that usually arises from the converging action of several pathogenic processes, including hypertension, hyperlidemia, obesity and insulin resistance. Significantly, due to the increasing incidence of type 2 diabetes worldwide, several aspects of the renin-angiotensin system, including the capacity for
Ulrich Kintscher
openalex +3 more sources