Results 51 to 60 of about 41,660 (152)

GC-MS and molecular docking studies of Hunteria umbellata methanolic extract as a potent anti-diabetic

Informatics in Medicine Unlocked, 2018
Background: The purpose of this study was to investigate the diabetic effect of phytocompounds synthesized from Hunteria umbellata using GC-MS analysis and molecular docking studies.
Olusola Abiola Ladokun, Aminu Abiola, Durosinlorun Okikiola, Famuti Ayodeji   +3 more
doaj   +1 more source

PPAR-gamma Signaling in Metabolic Homeostasis

Indonesian Biomedical Journal, 2016
INTRODUCTION: Peroxisome proliferator-activated receptor (PPAR)-γ, or also known as nuclear receptor subfamily 1 group C member 3 (NR1C3), is a PPAR which serves as master regulator of adipocytes differentiation, and plays an important role in lipid ...
Rina Triana, Nurrani Mustika Dewi, Siska Darmayanti, Eka Herawati, Maria Novalentina, Made Putra Semadhi, Miftakh Nur Rahman   +6 more
doaj   +1 more source

Ferroptosis and PPAR-gamma in the limelight of brain tumors and edema. [PDF]

Front Oncol, 2023
Yakubov E, Schmid S, Hammer A, Chen D, Dahlmanns JK, Mitrovic I, Zurabashvili L, Savaskan N, Steiner HH, Dahlmanns M.   +9 more
europepmc   +1 more source

PPAR Gamma Receptor: A Novel Target to Improve Morbidity in Preterm Babies. [PDF]

Pharmaceuticals (Basel), 2023
Victor S, Forbes B, Greenough A, Edwards AD.   +3 more
europepmc   +1 more source

PPAR-gamma in the Cardiovascular System.

PPAR research, 2011
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma), an essential transcriptional mediator of adipogenesis, lipid metabolism, insulin sensitivity, and glucose homeostasis, is increasingly recognized as a key player in inflammatory cells and in cardiovascular diseases (CVD) such as hypertension, cardiac hypertrophy, congestive heart failure ...
Sheng Zhong, Duan, Christine Y, Ivashchenko, Michael G, Usher, Richard M, Mortensen   +3 more
openaire   +1 more source

Anti-Diabetic Effect of Telmisartan Through its Partial PPARγ-Agonistic Activity

Diabetes, Metabolic Syndrome and Obesity, 2020
Muluken Altaye Ayza, Kaleab Alemayehu Zewdie, Bekalu Amare Tesfaye, Selamawit Tesfamariam Gebrekirstos, Derbew Fikadu Berhe Department of Pharmacology and Toxicology, School of Pharmacy, Mekelle University, Mekelle, EthiopiaCorrespondence: Muluken Altaye
Ayza MA, Zewdie KA, Tesfaye BA, Gebrekirstos ST, Berhe DF   +4 more
doaj  

PPAR-gamma agonist pioglitazone recovers mitochondrial quality control in fibroblasts from PITRM1-deficient patients. [PDF]

Front Pharmacol, 2023
Di Donfrancesco A, Berlingieri C, Giacomello M, Frascarelli C, Magalhaes Rebelo AP, Bindoff LA, Reeval S, Renbaum P, Santorelli FM, Massaro G, Viscomi C, Zeviani M, Ghezzi D, Bottani E, Brunetti D.   +14 more
europepmc   +1 more source

PPAR-Gamma Orchestrates EMT, AGE, and Cellular Senescence Pathways in Colonic Epithelium and Restrains the Progression of IBDs. [PDF]

Int J Mol Sci, 2023
Pompili S, Vetuschi A, Latella G, Smakaj A, Sferra R, Cappariello A.   +5 more
europepmc   +1 more source

Molecular docking of ferulic acid, bakuchiol and niazirin on peroxisome proliferator-activated receptor gamma (PPAR-γ) as anti-diabetic agents

Acta Biochimica Indonesiana
Background: Diabetes mellitus remains one of the most dangerous illnesses worldwide. The PPAR-gamma protein plays a crucial role in lipid and carbohydrate metabolism, making it a key target for diabetes therapy.
Anjar Hermadi Saputro, Riri Fauziyya, Sarmoko, Iwan Syahjoko Saputra   +3 more
doaj   +1 more source

Targeting PPAR-gamma counteracts tumour adaptation to immune-checkpoint blockade in hepatocellular carcinoma. [PDF]

Gut, 2023
Xiong Z, Chan SL, Zhou J, Vong JSL, Kwong TT, Zeng X, Wu H, Cao J, Tu Y, Feng Y, Yang W, Wong PP, Si-Tou WW, Liu X, Wang J, Tang W, Liang Z, Lu J, Li KM, Low JT, Chan MW, Leung HHW, Chan AWH, To KF, Yip KY, Lo YMD, Sung JJ, Cheng AS.   +27 more
europepmc   +1 more source