Results 61 to 70 of about 76,534 (232)

Deletion of PPAR-γ in immune cells enhances susceptibility to antiglomerular basement membrane disease

open access: yesJournal of Inflammation Research, 2010
Cristen Chafin2, Sarah Muse2, Raquel Hontecillas5, Josep Bassaganya-Riera5, David L Caudell2, Samuel K Shimp III4, M Nichole Rylander4, John Zhang6, Liwu Li3, Christopher M Reilly1,21Virginia College of Osteopathic Medicine, 2Department of Biomedical ...
Cristen Chafin   +3 more
doaj  

Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention?

open access: yesCardiovascular Diabetology, 2012
All fibrates are peroxisome proliferators-activated receptors (PPARs)-alpha agonists with ability to decrease triglyceride and increase high density lipoprotein- cholesterol (HDL-C).
Tenenbaum Alexander, Fisman Enrique Z
doaj   +1 more source

Topical rosiglitazone is an effective anti-scarring agent in the cornea [PDF]

open access: yes, 2013
Corneal scarring remains a major cause of blindness world-wide, with limited treatment options, all of which have side-effects. Here, we tested the hypothesis that topical application of Rosiglitazone, a Thiazolidinedione and ligand of peroxisome ...
Bühren, Jens   +8 more
core   +7 more sources

Emerging role of the peroxisome proliferator-activated receptor-gamma in hepatocellular carcinoma

open access: yesJournal of Hepatocellular Carcinoma, 2014
Hui-Tzu Hsu,1 Chin-Wen Chi1,21Department and Institute of Pharmacology, School of Medicine, National Yang-Ming University, Taipei, Taiwan; 2Department of Medical Research, Taipei Veterans General Hospital, Taipei, TaiwanAbstract: Hepatocellular carcinoma
Hsu HT, Chi CW
doaj  

Soy milk and ginger (Sulehe) increase PPAR-γ expression in a rat model of insulin resistance

open access: yesСахарный диабет, 2018
Background: Diabetes mellitus type 2 is metabolic disease characterized by hyperglycemia due to a defect in insulin secretion resulting in insulin resistance. This disease leads to dysfunction of various organs including eyes, kidneys, and heart.
Wiwik Handayani   +3 more
doaj   +1 more source

Effects Of PPARγ2 Pro12Ala Variant On Adipocyte Phenotype Dependent Of DHA

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2019
Renhui Wan,* Zhengping Ding,* Sheng Xia, Longyi Zheng, Jin Lu Department of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai 200433, People’s Republic of China*These authors contributed equally to this ...
Wan R, Ding Z, Xia S, Zheng L, Lu J
doaj  

Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma

open access: yesFrontiers in Physiology, 2017
Gliomas cells are the site of numerous metabolic and thermodynamics abnormalities with an increasing entropy rate which is characteristic of irreversible processes driven by changes in Gibbs energy, heat production, intracellular acidity, membrane ...
Alexandre Vallée   +5 more
doaj   +1 more source

Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice [PDF]

open access: yes, 2017
Trypanosoma cruzi infection induces an intense inflammatory response in diverse host tissues. The immune response and the microvascular abnormalities associated with infection are crucial aspects in the generation of heart damage in Chagas disease.
Carta, Davide   +9 more
core   +2 more sources

Synergism in hyperhomocysteinemia and diabetes: role of PPAR gamma and tempol

open access: yesCardiovascular Diabetology, 2010
Background Hyperhomocysteinemia (HHcy) and hyperglycemia cause diabetic cardiomyopathy by inducing oxidative stress and attenuating peroxisome proliferator- activated receptor (PPAR) gamma. However, their synergistic contribution is not clear.
Mishra Paras K   +4 more
doaj   +1 more source

What makes gouty inflammation so variable? [PDF]

open access: yes, 2017
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Terkeltaub, Robert
core   +2 more sources

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