Ppar signaling pathway - Open Access .click

Journal of Biochemical and Molecular Toxicology
ABSTRACTWith the gradual emergence of xylazine as a street drug, incidents of xylazine poisoning are now occurring worldwide. However, it remains unknown whether long‐term exposure to xylazine causes nonalcoholic fatty liver disease (NAFLD). In the present study, the rats were injected with xylazine intraperitoneally for 28 consecutive days, and then ...
Shuquan Zhao, Shanyong Yi
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Targeting PPARs Signaling Pathways in Cardiotoxicity by Natural Compounds

Cardiovascular Toxicology, 2022
Cardiotoxicity can be a complication of both drugs and a variety of other chemicals that affects morbidity, quality of life, and even mortality. The accumulation of lipids and inflammation have been implicated in the development of cardiotoxicity. The peroxisome proliferator-activated receptors (PPARs), a family of transcription factors, have a role in
Fatemeh Yarmohammadi, A. Wallace Hayes, Gholamreza Karimi +2 more
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Proteomics Analysis Reveals an Important Role for the PPAR Signaling Pathway in DBDCT-Induced Hepatotoxicity Mechanisms

Molecules, 2017
A patented organotin di-n-butyl-di-(4-chlorobenzohydroxamato)tin (DBDCT) with high a antitumor activity was designed, however, its antitumor and toxic mechanisms have not yet been clearly illustrated.
Yunlan Li, Qing Shan Li
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PPAR Tissue Distribution and Interactions with Other Hormone‐Signaling Pathways^a

Annals of the New York Academy of Sciences, 1996
Reference NCEM-REVIEW-1996-006doi:10.1111/j.1749-6632.1996.tb18619.xView record in PubMed Record created on 2009-04-02, modified on 2017-05 ...
Lemberger T +9 more
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signal transduction
3. good health
animals

ppar gamma
humans
peroxisome proliferator-activated receptors

male
mice
liver