Results 31 to 40 of about 1,756 (151)

The association of polymorphisms in the ovine PPARGC1B and ZEB2 genes with body weight in Hu sheep

Animal Biotechnology, 2020
The aims of this study were to analyze the effects of PPARGC1B and ZEB2 polymorphisms on the body weight of Hu sheep. DNA sequencing and KASPar technologies were used to detect single nucleotide polymorphisms (SNPs) within the PPARGC1B and ZEB2 genes of Hu sheep (n = 207). Two synonymous mutations, g.300 G > A and g.645 C > T, were detected in PPARGC1B
Deyin, Zhang, Xiaoxue, Zhang, Fadi, Li, Yongfu, La, Guoze, Li, Yukun, Zhang, Xiaolong, Li, Yuan, Zhao, Qizhi, Song, Weimin, Wang   +9 more
openaire   +2 more sources

The Role of Peroxisome Proliferator-Activated Receptors (PPARs) in Pan-Cancer

PPAR Research, 2020
Peroxisome proliferator-activated receptors (PPARs) are members of nuclear transcription factors. The functions of the PPAR family (PPARA, PPARD, and PPARG) and their coactivators (PPARGC1A and PPARGC1B) in maintenance of lipid and glucose homeostasis ...
Runzhi Huang, Jiaqi Zhang, Mingxiao Li, Penghui Yan, Huabin Yin, Suna Zhai, Xiaolong Zhu, Peng Hu, Jiaxin Zhang, Ling Huang, Man Li, Zehui Sun, Tong Meng, Daoke Yang, Zongqiang Huang   +14 more
doaj   +1 more source

Identification of the Functions and Prognostic Values of RNA Binding Proteins in Bladder Cancer

Frontiers in Genetics, 2021
Post-transcriptional regulation plays a leading role in gene regulation and RNA binding proteins (RBPs) are the most important posttranscriptional regulatory protein.
Yue Wu, Yue Wu, Zheng Liu, Zheng Liu, Xian Wei, Xian Wei, Huan Feng, Huan Feng, Bintao Hu, Bintao Hu, Bo Liu, Yang Luan, Yang Luan, Yajun Ruan, Yajun Ruan, Xiaming Liu, Xiaming Liu, Zhuo Liu, Zhuo Liu, Shaogang Wang, Shaogang Wang, Jihong Liu, Jihong Liu, Tao Wang, Tao Wang   +24 more
doaj   +1 more source

PPARG rs3856806 C>T Polymorphism Increased the Risk of Colorectal Cancer: A Case-Control Study in Eastern Chinese Han Population

Frontiers in Oncology, 2019
Purpose: Functional variants in the peroxisome proliferator-activated receptor gamma (PPARG) and PPARG co-activator 1 (PPARGC1) family (e.g., PPARGC1A and PPARGC1B) genes were predicted to confer susceptibility to colorectal cancer (CRC).
Jing Lin, Jing Lin, Yu Chen, Yu Chen, Yu Chen, Wei-feng Tang, Chao Liu, Sheng Zhang, Zeng-qing Guo, Zeng-qing Guo, Zeng-qing Guo, Gang Chen, Gang Chen, Xiong-wei Zheng, Xiong-wei Zheng   +14 more
doaj   +1 more source

Telomerase reverse transcriptase (TERT); peroxisome proliferation–activated receptor-γ coactivator 1β (PPARGC1B; PGC-1β) [PDF]

Science-Business EXchange, 2012
exaly   +2 more sources

Adipose tissue-specific ablation of PGC-1β impairs thermogenesis in brown fat

Disease Models & Mechanisms, 2022
Impaired thermogenesis observed in mice with whole-body ablation of peroxisome proliferator-activated receptor-γ coactivator-1β (PGC-1β; officially known as PPARGC1B) may result from impaired brown fat (brown adipose tissue; BAT) function, but other ...
Jiří Funda, Josep A. Villena, Kristina Bardova, Katerina Adamcova, Illaria Irodenko, Pavel Flachs, Ivana Jedlickova, Eliska Haasova, Martin Rossmeisl, Jan Kopecky, Petra Janovska   +10 more
doaj   +1 more source

Genetic effect of single‐nucleotide polymorphisms in the PPARGC1B gene on airway hyperreactivity in asthmatics

The FASEB Journal, 2011
Peroxisome proliferator‐activated receptor gamma coactivator 1 beta (PPARGC1B) is a co‐activator for intracellular receptors such as the ER, PPAR, and GR, which are involved in asthma development. Association of single‐nucleotide polymorphisms (SNPs) in PPARGC1B gene with risk of asthma and airway hyperreactivity (AHR) was investigated.
Shin‐Hwa Lee, An‐Soo Jang, Sung Woo Park, Jong‐Sook Park, Yang Ki Kim, Soo‐Taek Uh, Yong Hoon Kim, Yup Chung, Byung‐Lae Park, Hyung Doo Shin, Choon‐Sik Park   +10 more
openaire   +1 more source

Construction and validation of an RNA-binding protein-associated prognostic model for colorectal cancer [PDF]

PeerJ, 2021
Colorectal cancer (CRC) is one of the most prevalent and fatal malignancies, and novel biomarkers for the diagnosis and prognosis of CRC must be identified. RNA-binding proteins (RBPs) are essential modulators of transcription and translation.
Yandong Miao, Hongling Zhang, Bin Su, Jiangtao Wang, Wuxia Quan, Qiutian Li, Denghai Mi   +6 more
doaj   +2 more sources

The association of Single Nucleotide Polymorphisms of PPARGC1B with AHR in asthmatic patients

The FASEB Journal, 2008
PPARGC1B is a co‐activator for ER, PPAR, and GR, which are involved in asthma development. We investigated the genetic association of PPARGC1B polymorphisms with the risk of asthma and subphenotypes and the functional effect of these polymorphisms on the expression of PPARGC1B. Through direct DNA sequencing for PPARGC1B on chromosome 5q33 of 24 Koreans,
Shin‐Hwa Lee, Ju Hyun Park, Hun Soo Chung, Soo‐Taek Uh, Young Hoon Kim, Jong‐Sook Park, Ki‐Hyun Seo, Joo Ok Na, Tai youn Rhim, Byung‐Lae Park, Choon‐Sik Park, Hyung Doo Shin, Il‐Yup Chung   +12 more
openaire   +1 more source

Global investigation of estrogen-responsive genes regulating lipid metabolism in the liver of laying hens

BMC Genomics, 2021
Background Estrogen plays an essential role in female development and reproductive function. In chickens, estrogen is critical for lipid metabolism in the liver. The regulatory molecular network of estrogen in chicken liver is poorly understood.
Junxiao Ren, Weihua Tian, Keren Jiang, Zhang Wang, Dandan Wang, Zhuanjian Li, Fengbin Yan, Yanbin Wang, Yadong Tian, Kepeng Ou, Hongjun Wang, Xiangtao Kang, Hong Li, Xiaojun Liu   +13 more
doaj   +1 more source