Results 141 to 150 of about 4,765 (208)

Важность (p) ppGpp как регулятора выживания бактерий обусловила необходимость создания антибиотика Relacin, который является негидролизуемым аналогом ppGpp и ингибирует его биосинтез (по [Wexselblatt, 2012; Seal, 2017])

, 2021
Важность (p) ppGpp как регулятора выживания бактерий обусловила необходимость создания антибиотика Relacin, который является негидролизуемым аналогом ppGpp и ингибирует его биосинтез (по [Wexselblatt, 2012; Seal, 2017]
Андрюков БГ
core   +1 more source

The ppGpp-HpaR1-gum regulatory pathway modulates exopolysaccharides production in Xanthomonas campestris pv. campestris

npj Biofilms and Microbiomes
Exopolysaccharides (EPS) are critical components of the biofilm matrix, and ppGpp has been demonstrated to positively influence biofilm formation. Here, we elucidate the underlying mechanism by which ppGpp regulates EPS production by facilitating HpaR1 ...
Kaihong Bai, Xiaoli Xu, Chengxuan Yu, Huayu Yan, Miaomiao Lyu, Na Jiang, Jianqiang Li, Jingnan Zhang, Zhenlong Wang, Laixin Luo   +9 more
doaj   +1 more source

Growth suppression by altered (p)ppGpp levels results from non-optimal resource allocation in Escherichia coli

Nucleic Acids Research, 2019
Understanding how bacteria coordinate gene expression with biomass growth to adapt to various stress conditions remains a grand challenge in biology. Stress response is often associated with dramatic accumulation of cellular guanosine tetra- or penta ...
Manlu Zhu, Xiongfeng Dai
semanticscholar   +1 more source

ppGpp Formation in Escherichia coli Treated with Rifampicin

Journal of Biological Chemistry, 1971
Abstract It has been previously reported that the accumulation of the regulatory nucleotide ppGpp (MS I), which is governed by the RC gene of Escherichia coli, does not occur in the presence of rifampicin. Since this drug inhibits RNA chain initiation, it was suggested that the formation of ppGpp is somehow dependent on the presence of nascent RNA ...
H, Erlich, T, Laffler, J, Gallant
openaire   +2 more sources

Cidades Rebeldes: apropriação dos espaços públicos e os movimentos sociais urbanos

Conversas & Controvérsias, 2018
RESENHA: David HARVEY. Cidades rebeldes: do direito à cidade à revolução urbana. São Paulo: Martins Fontes, 2014.
Julia Giles Wünsch
doaj  

Comparative proteomic analysis of Salmonella enterica serovar Typhimurium ppGpp-deficient mutant to identify a novel virulence protein required for intracellular survival in macrophages

BMC Microbiology, 2010
Background The global ppGpp-mediated stringent response in pathogenic bacteria plays an important role in the pathogenesis of bacterial infections. In Salmonella enterica serovar Typhimurium (S. Typhimurium), several genes, including virulence genes, are
Kumagai Yoshinori, Miki Tsuyoshi, Shimizu-Izumi Satomi, Maeda Tadakazu, Oh-Ishi Masamichi, Kodera Yoshio, Yoshida-Ohta Yukie, Sugimoto Mariko, Haneda Takeshi, Danbara Hirofumi, Okada Nobuhiko   +10 more
doaj   +1 more source

Development of in vivo ppGpp reporters in escherichia coli [PDF]

, 2018
ppGpp is a small molecule that works as a global master regulator of the E. coli physiology, most notably during the stringent response. Systems biology studies have emphasized its role in understanding the host response to the burden of introduced ...
Li, Jinbei Walden
core  

Implicações do neoliberalismo na garantia de direitos da pessoa humana em saúde mental: Uma análise a partir do contexto da política pública de saúde mental brasileira

Revista Direitos Humanos e Democracia
O presente artigo tem como tema o direito humano à saúde mental, delimitado no objeto das implicações do neoliberalismo na garantia de direitos da pessoa humana em saúde mental.
Ruan Didier Bruzaca, Claudineide Alves dos Santos   +1 more
doaj   +1 more source

(p)ppGpp quantification.

, 2015
A. Wild type or relA mutant strains grown at 37°C in the MOPS derivative medium with or without arginine hydroxamate (100 μg/ml) were labeled with H332PO4 for 4 to 5 generations.
Etienne Dervyn (730354), Cyprien Guérin (2586016), Camille Benoist (822757), Philippe Noirot (44983)   +3 more
core   +1 more source

The synthesis and function of the alarmone (p)ppGpp in firmicutes

International Journal of Medical Microbiology, 2010
In most bacteria, nutrient limitations provoke the stringent control by the rapid synthesis of the alarmones pppGpp and ppGpp. The most prominent and highly conserved reaction is the repression of rRNA synthesis. Additionally, (p)ppGpp synthesis is also linked to many other physiological changes involving gene activation/repression but also protein ...
Christiane, Wolz, Tobias, Geiger, Christiane, Goerke   +2 more
openaire   +2 more sources