Results 151 to 160 of about 7,972 (181)
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Lack of accumulation of ppGpp in sea urchin embryos
Developmental Biology, 1976Abstract Sea urchin eggs and embryos of a variety of stages were labeled with [ 32 P]orthophosphate. We have been unable to detect the accumulation of guanosine tetraphosphate (Magic Spot I) at any stage. We point out a potential artifact in screening cells for the synthesis of Magic Spot. I.
B, Brandhorst, D, Fromson
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The mechanism of action of ppGpp on rRNA synthesis in vitro
Cell, 1976We have studied the mechanism of the specific inhibition of ribosomal RNA synthesis by ppGpp in a purified system using as templates E. coli DNA and DNA from lambdad5ilv, which carries a rRNA cistron from E. coli. Ribosomal RNA synthesis, as well as its inhibition by ppGpp, are critically salt-dependent. Of a number of guanosine phosphates tested, only
van Ooyen, A J +2 more
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Kinetic suppression of translational errors by (p)ppGpp
Molecular and General Genetics MGG, 1982The effect of (p)ppGpp on the accuracy of translation was studied in vitro using a poly(U)-programmed poly(Phe)-synthesizing system operating at incorporation rates and missense error frequencies close to the values obtained in vivo. Simulation of a relaxed phenotype in vitro was accomplished by limitation of the cognate aminoacyl-tRNA synthetase ...
E. Gerhart +3 more
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Microbiology and Molecular Biology Reviews
SUMMARY Bacteria are constantly exposed to changing environmental conditions, and to survive they need to adapt quickly, adjusting their gene expression and metabolism to make the most of the resources available. One of the mechanisms involved is the stringent response, characterized by production of specific guanosine derivatives ...
Katarzyna Potrykus +3 more
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SUMMARY Bacteria are constantly exposed to changing environmental conditions, and to survive they need to adapt quickly, adjusting their gene expression and metabolism to make the most of the resources available. One of the mechanisms involved is the stringent response, characterized by production of specific guanosine derivatives ...
Katarzyna Potrykus +3 more
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A tRNATyr promoter with an altered in vitro response to ppGpp
Journal of Molecular Biology, 1980A synthetic alteration in the promoter sequence of the tRNA Tyr gene from (Ryan et al. , 1979) alters the in vitro regulation of the promoter by ppGpp such that synthesis of RNA from the mutant promoter responds to increasing concentrations of ppGpp in a reciprocal manner to that from the wild-type promoter.
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ppGpp: stringent response and survival.
Journal of microbiology (Seoul, Korea), 2006Adaptation to any undesirable change in the environment dictates the survivability of many microorganisms, with such changes generating a quick and suitable response, which guides the physiology of bacteria. During nutritional deprivation, bacteria show a stringent response, as characterized by the accumulation of (p)ppGpp, resulting in the repression ...
Jain, Vikas +2 more
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Two P or Not Two P: Understanding Regulation by the Bacterial Second Messengers (p)ppGpp
Annual Review of Microbiology, 2021Anastasia Liuzzi +2 more
exaly
Role of (p)ppGpp in antibiotic resistance, tolerance, persistence and survival in Firmicutes
MicroLife, 2023Andrea Salzer, Christiane Wolz
exaly
ppGpp influences protein protection, growth and photosynthesis in Phaeodactylum tricornutum
New Phytologist, 2021Sylvie Citerne +2 more
exaly