ppGpp signaling plays a critical role in virulence of Acinetobacter baumannii
, 2021 Acinetobacter baumannii, a major nosocomial pathogen, survives in diverse hospital environments, and its multidrug resistance is a major concern. The ppGpp-dependent stringent response mediates the reprogramming of genes with diverse functions in several
Minsang Shin (7235846) +8 more
core +1 more source
Guanosine tetraphosphate (ppGpp) is a new player in Brassica napus L. seed development
International audienceRapeseed oil, constituting 12% of global vegetable oil production, is susceptible to quality degradation due to stress-induced incomplete seed degreening, fatty acid oxidation, or poor nutrient accumulation.
Dąbrowska, Grażyna, B +19 more
core +1 more source
Affinity-based capture and identification of protein effectors of the growth regulator ppGpp
Nature Chemical Biology, 2018 The nucleotide ppGpp is a highly conserved regulatory molecule in bacteria that helps tune growth rate to nutrient availability. Despite decades of study, how ppGpp regulates growth remains poorly understood.
Boyuan Wang +6 more
semanticscholar +1 more source
Selective Fluorescent Chemosensor for the Bacterial Alarmone (p)ppGpp
, 2016 We have developed the first selective fluorescent chemosensor (PyDPA) for (p)ppGpp, a bacterial and plant alarmone. By using pyrene-excimer fluorescence, PyDPA shows very good selectivity for (p)ppGpp from among other nucleotides in water. PyDPA was used
Young-Jae Seok (2457913) +7 more
core +1 more source
Em defesa dos direitos sociais: A luta pela proteção e pela liberdade em cenários voláteis
Revista Direitos Humanos e DemocraciaA proposta do estudo é discutir sobre as repercussões que incidem sobre os direitos sociais a partir de uma concepção assentada nas relações constituídas entre Estado e sociedade, tomando como ponto de partida o regime democrático brasileiro e as ...
Jairo de Carvalho Guimarães +1 more
doaj +1 more source
Distinct roles of ppGpp and DksA in Legionella pneumophila differentiation
, 2010 To transit between hosts, intracellular Legionella pneumophila transform into a motile, infectious, transmissive state. Here we exploit the pathogen's life cycle to examine how guanosine tetraphosphate (ppGpp) and DksA cooperate to govern bacterial ...
Dalebroux, Zachary D. +4 more
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(p)ppGpp and manganese homeostasis supplementary
, 2019 Supplementary data to "Association of Metal Homeostasis and (p)ppGpp Regulation in the Pathophysiology of Enterococcus faecalis.
José A. Lemos (239435) +2 more
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Identification of novel ppGpp-interaction partners in \(\textit {Escherichia coli}\)
, 2023 (p)ppGpp ist ein ubiquitär in Bakterien und Chloroplasten vorkommendes Alarmon. Intrazelluläre Akkumulation des sekundären Botenstoffes vermitteln pleiotrope Anpassungen an Nährstoffmangel durch direkte Interaktion mit Proteinen, wie der RNA Polymerase.
Müller, Fabian (M. Sc.)
core
HPLC põhine regulaatornukleotiidide (p)ppGpp ja ppApp tasemete analüüs bakterirakus [PDF]
, 2020 Väitekirja elektrooniline versioon ei sisalda publikatsiooneBakteritel on evolutsiooni käigus välja kujunenud arvukalt kohanemismehhanisme, mis aitavad neil ellu jääda ka karmides keskkonnatingimustes.
Alves Oliveira, Sofia Raquel
core
The mediator for stringent control, ppGpp, binds to the β-subunit of Escherichia coli RNA polymerase
, 1998 Background Inhibition of transcription of rRNA in Escherichia coli upon amino acid starvation is thought to be due to the binding of ppGpp to RNA polymerase. However, the nature of this interaction still remains obscure.
Chatterji, Dipankar +2 more
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