Results 131 to 140 of about 4,765 (208)
Guanosine tetraphosphate (ppGpp) signalling promotes high-light tolerance in Arabidopsis thaliana
Guanosine tetraphosphate (ppGpp) is a hyperphosphorylated nucleotide originally discovered in prokaryotes and found in the chloroplasts of plants and algae.
Nawrocki, Wojciech +12 more
core +1 more source
Frontiers in Microbiology, 2018 During the diauxic shift, Escherichia coli exhausts glucose and adjusts its expression pattern to grow on a secondary carbon source. Transcriptional profiling studies of glucose–lactose diauxic transitions reveal a key role for ppGpp. The amount of ppGpp
Llorenç Fernández-Coll, Michael Cashel
doaj +1 more source
Nanozymes Integrated Biochips Toward Smart Detection System
Advanced Science, Volume 13, Issue 11, 23 February 2026.This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen +10 more
wiley +1 more source
Crucial Role of ppGpp in the Resilience of
mSphere, 2020 Bacteria grow in constantly changing environments that can suddenly become completely depleted of essential nutrients. The stringent response, a rewiring of the cellular metabolism mediated by the alarmone (p)ppGpp, plays a crucial role in adjusting ...
Clément Patacq +2 more
doaj +1 more source
Epitranscriptomics as a Candidate Universal Modulator of Dormancy Transitions
Ecology and Evolution, Volume 16, Issue 2, February 2026.Dormancy is presented as a conserved, reversible survival program in which epitranscriptomic RNA modifications are proposed to provide a rapid, energy‐efficient layer that establishes, maintains, and terminates the state by modulating mRNA stability, translation, and localization.
Ehsan Pashay Ahi
wiley +1 more source
Selective fluorescent chemosensor for the bacterial alarmone (p)ppGpp
, 2015 We have developed the first selective fluorescent chemosensor (PyDPA) for (p)ppGpp, a bacterial and plant alarmone. By using pyrene-excimer fluorescence, PyDPA shows very good selectivity for (p)ppGpp from among other nucleotides in water. PyDPA was used
Song, Mi-Ryung +7 more
core +1 more source
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah +8 more
wiley +1 more source
The Study of a Novel (p)ppGpp Synthase (YwaC) from Bacillus subtilis 168
, 2008 Adaptation to any undesirable change in the environment helps to ensure the survival of many microorganisms. During nutrient starvation, bacteria undergo a stringent response characterized by the accumulation of the alarmone (p)ppGpp.
Dalgleish, Heather
core
A comprehensive analysis of (p)ppGpp signaling in bacteria
(p)ppGpp is a signaling molecule produced by bacteria in response to stresses, particularly amino acid starvation. RelA/SpoT homolog (RSH) enzymes synthesize (p)ppGpp when an uncharged tRNA enters an actively translating ribosome, stalling protein ...
Hydorn, Molly Anne
core +1 more source
Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis
, 2009 We report that larvae of the wax moth (Galleria mellonella) are susceptible to infection with the human enteropathogen Yersinia pseudotuberculosis at 37 degrees C. Confocal microscopy demonstrated that in the initial stages of infection the bacteria were
Champion, Olivia L +10 more
core +1 more source