NmPin from the marine thaumarchaeote Nitrosopumilus maritimus is an active membrane associated prolyl isomerase. [PDF]
, 2016 We cordially thank Alma Rute for excellent technical assistance and the DFG (GRK 1431-1 and 1431-2) for financial support (PB). We thank the Microscope and Histology Facility of the University of Aberdeen for providing their equipment.
Bayer, Peter +5 more
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Molecular docking analysis of juglone with parvulin-type PPiase PrsA from Staphylococcus aureus
Bioinformation, 2023 Staphylococcus aureus is an opportunistic pathogen that causes variety of infections range from mild skin diseases to life-threatening sepsis. It is also notorious for acquiring resistance to numerous antibiotics. Parvulin-type peptidyl-prolyl cis-trans isomerase (PPiase) domain containing PrsA protein is considered as an essential folding factor for ...
Dipten, Laskar +2 more
openaire +2 more sources
The Periplasmic Chaperone Network of Campylobacter jejuni: Evidence that SalC (Cj1289) and PpiD (Cj0694) Are Involved in Maintaining Outer Membrane Integrity [PDF]
, 2017 The outer membrane (OM) of Gram-negative pathogenic bacteria is a key structure in host–pathogen interactions that contains a plethora of proteins, performing a range of functions including adhesion, nutrient uptake, export of effectors and interaction ...
Asakura +45 more
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BMC Plant Biology, 2019 Background Cyclophilins (CYPs), belonging to the peptidyl prolyl cis/trans isomerase (PPIase) superfamily, play important roles during plant responses to biotic and abiotic stresses.
Jun Yang +8 more
doaj +1 more source
The human FK506-binding proteins: characterization of human FKBP19 [PDF]
, 2006 Analysis of the human repertoire of the FK506-binding protein (FKBP) family of peptidyl-prolyl cis/trans isomerases has identified an expansion of genes that code for human FKBPs in the secretory pathway.
A Galat +43 more
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FKBP51 and FKBP52 in signaling and disease [PDF]
, 2011 FKBP51 and FKBP52 are diverse regulators of steroid hormone receptor signaling, including receptor maturation, hormone binding and nuclear translocation.
Cox, Marc B. +4 more
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A cavity with an appropriate size is the basis of the PPIase activity [PDF]
Protein Engineering Design and Selection, 2008 Peptidyl-prolyl isomerases (PPIases) are biologically very important enzymes but their catalytic mechanism is not fully understood. Recently, our comprehensive mutational study on a PPIase, human FK506-binding protein 12 (FKBP12), suggested that only presence of a cavity was required for the catalysis.
Teikichi, Ikura +2 more
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Pin1 modulates the type 1 immune response. [PDF]
PLoS ONE, 2007 BACKGROUND/ABSTRACT: Immune responses initiated by T cell receptor (TCR) and costimulatory molecule mediated signaling culminate in maximal cytokine mRNA production and stability.
Stephane Esnault +7 more
doaj +1 more source
Proteomic identification of OsCYP2, a rice cyclophilin that confers salt tolerance in rice (
, 2011 Background High Salinity is a major environmental stress influencing growth and development of rice. Comparative proteomic analysis of hybrid rice shoot proteins from Shanyou 10 seedlings, a salt-tolerant hybrid variety, and Liangyoupeijiu seedlings, a ...
Tong Jian-Xin +9 more
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The novel missense mutation Met48Lys in FKBP22 changes its structure and functions. [PDF]
, 2020 Mutations in the FKBP14 gene encoding FKBP22 (FK506 Binding Protein 22 kDa) cause kyphoscoliotic Ehlers-Danlos Syndrome (kEDS). The first clinical report showed that a lack of FKBP22 protein due to mutations causing nonsense-mediated decay of the mRNA ...
Bächinger, Hans Peter +7 more
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