Control of plant phosphate homeostasis by inositol pyrophosphates and the SPX domain. [PDF]
Proteins containing a SPX domain are involved in phosphate (Pi) homeostasis, including Pi transport and adaptation to Pi deficiency. The SPX domain harbors a basic surface binding Pi at low affinity and inositol pyrophosphates (PP-InsPs) at high affinity.
Hothorn, M.+3 more
core +1 more source
Role of transporters in regulating mammalian intracellular inorganic phosphate. [PDF]
Jennings ML.
europepmc +1 more source
Harnessing {13}^C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR [PDF]
Inositol poly- and pyrophosphates (InsPs and PP-InsPs) are an important group of metabolites and mediate a wide range of processes in eukaryotic cells. To elucidate the functions of these molecules, robust techniques for the characterization of inositol ...
Fiedler, D+5 more
core
The Inositol Phosphate System-A Coordinator of Metabolic Adaptability. [PDF]
Tu-Sekine B, Kim SF.
europepmc +1 more source
Identification of a functional nuclear translocation sequence in hPPIP5K2 [PDF]
core +1 more source
Characterization of Inorganic Polyphosphate in Mammalian Cells [PDF]
Inorganic polyphosphate (polyP) is a linear chain of three to around one thousand orthophosphates linked by phosphoanhydride bonds. Not only is polyP considered as a “molecular fossil” that existed on the primordial earth, but it is also universally ...
Xie, Lihan
core
ITPK1 Regulates Jasmonate-Controlled Root Development in Arabidopsis thaliana. [PDF]
Pullagurla NJ, Shome S, Yadav R, Laha D.
europepmc +1 more source
Development of a yeast model to study the contribution of vacuolar polyphosphate metabolism to lysine polyphosphorylation [PDF]
A recently discovered protein post-translational modification, lysine polyphosphorylation (K-PPn), consists of the covalent attachment of inorganic polyphosphate (polyP) to lysine residues.
Azevedo, C+8 more
core
Depleting inositol pyrophosphate 5-InsP7 protected the heart against ischaemia–reperfusion injury by elevating plasma adiponectin [PDF]
Aims Adiponectin is an adipocyte-derived circulating protein that exerts cardiovascular and metabolic protection. Due to the futile degradation of endogenous adiponectin and the challenges of exogenous administration, regulatory mechanisms of adiponectin
Aguirre, Tim+12 more
core +2 more sources