Results 51 to 60 of about 3,727 (217)

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, Volume 208, Issue 6, Page 1980-1992, June 2026.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

Heterogeneous Reconstitution of the PQQ-Dependent Glucose Dehydrogenase Immobilized on an Electrode: A Sensitive Strategy for PQQ Detection Down to Picomolar Levels

, 2016
A highly sensitive electroanalytical method for determination of PQQ in solution down to subpicomolar concentrations is proposed. It is based on the heterogeneous reconstitution of the PQQ-dependent glucose dehydrogenase (PQQ-GDH) through the specific ...
François Mavré (1844383), Guobao Xu (1788382), Benoît Limoges (1570498), Claire Stines-Chaumeil (1844380), Rebeca Miranda-Castro (1664485), Nicolas Mano (1568131), Ling Zhang (18071)   +6 more
core   +1 more source

Bioelectrocatalytic activity of reconstituted peroxidase on hemin-terminated PQQ-modified electrodes

Sensors and Actuators Reports, 2022
Efficient direct electrical communication between an enzyme redox center and an electrode is of great interest from the viewpoints of application to reagentless biosensors and biofuel cells.
Kikuo Komori, Tomoki Aikawa
doaj   +1 more source

A ‘Genome‐First’ Framework for Next‐Generation Bioinputs: From Functional Mining to Rational Synthetic Microbial Communities

Environmental Microbiology, Volume 28, Issue 5, May 2026.
I propose a ‘genome‐first’ framework to collapse the phenotypic bottleneck in bioinput discovery. By integrating multi‐layered genome mining and reverse ecology, this paradigm enables the rational design of stable synthetic microbial communities for a data‐driven and sustainable agricultural bioeconomy.
Osiel Silva Gonçalves
wiley   +1 more source

Heterogeneous Reconstitution of the PQQ-Dependent Glucose Dehydrogenase Immobilized on an Electrode: A Sensitive Strategy for PQQ Detection Down to Picomolar Levels

, 2014
International audienceA highly sensitive electroanalytical method for determination of PQQ in solution down to subpicomolar concentrations is proposed.
Limoges, Benoît, Mano, Nicolas, Mavré, François, Zhang, Ling, Miranda-Castro, Rebeca, Stines-Chaumeil, Claire, Xu, Guobao   +6 more
core   +1 more source

Effects of pyrroloquinoline quinone and imidazole pyrroloquinoline on biological activities and neural functions

Heliyon, 2020
Pyrroloquinoline quinone (PQQ) is contained in fruits and vegetables and in human breast milk. It has been reported that PQQ has high reactivity and changes to an imidazole structure (imidazole pyrroloquinoline) by a reaction with an amino acid at a high
Yasue Yamada, Kazuya Nishii, Koji Kuwata, Masashi Nakamichi, Kei Nakanishi, Atsushi Sugimoto, Kazuto Ikemoto   +6 more
doaj   +1 more source

Nacre-inspired magnetically oriented micro-cellulose fibres/nano-hydroxyapatite/chitosan layered scaffold enhances pro-osteogenesis and angiogenesis

Materials Today Bio, 2022
In situ regeneration of large-segment bone defects is a difficult clinical problem. Here, we innovatively developed magnetically oriented micro-cellulose fibres using nano-hydroxyapatite/chitosan (CEF/Fe3O4/HA/CS) and loaded an NFκB pathway inhibitor on ...
Yu-Wei Ge, Min Chu, Zi-Yang Zhu, Qin-Fei Ke, Ya-Ping Guo, Chang-Qing Zhang, Wei-Tao Jia   +6 more
doaj   +1 more source

The Structure of a Biosynthetic Intermediate of Pyrroloquinoline Quinone (PQQ) and Elucidation of the Final Step of PQQ Biosynthesis

, 2016
Pyrroloquinoline quinone (PQQ) is a tricyclic o-quinone, which serves as a cofactor in several enzyme-catalyzed redox reactions in certain bacteria. PQQ is also important for human health, and its role as a vitamin in mammals has recently been suggested.
Megumi Saeki (2718427), Olafur T. Magnusson (418887), Robert Schwarzenbacher (45566), Judith P. Klinman (189488), Hirohide Toyama (2225839)   +4 more
core   +1 more source

Genetics and Regulation of Pyrroloquinoline Quinone (PQQ) Biosynthesis in the Methylotrophic Bacterium Methylobacterium extorquens AM1 [PDF]

, 1994
Pyrroloquinoline quinone (PQQ) has potential applications in the treatment of Alzheimers disease and jaundice. PQQ is produced and secreted in large amounts by methylotrophic bacteria, and they have potential for commercial PQQ production.
Ramamoorthi, Roopa
core   +1 more source

A Multicenter Trial of an Enhanced Serum Comprised of 13 Plant‐Based Adaptogens Targeting Skin Quality in Females Impacted by Hormonal Decline

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Objectives To assess the effectiveness and tolerability of a serum comprised of plant‐based adaptogens (MYS‐REV) for visible improvements in skin changes caused by hormonal fluctuations associated with perimenopause and postmenopause in women. Study Designs A 16‐week open‐label multicenter study evaluated the efficacy and tolerability of twice‐
Zoe D. Draelos, Amir Moradi, Amber Smathers   +2 more
wiley   +1 more source