A simulation-based approach to strengthen chronic wasting disease surveillance in captive cervid populations. [PDF]
PLoS OneWakefield L +4 more
europepmc +1 more source
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Practical Real-Time Quaking-Induced Conversion for Detecting Classical Bovine Spongiform Encephalopathy and Classical and Atypical Scrapie Prions. [PDF]
PathogensSuzuki A +8 more
europepmc +1 more source
Deep Mutational Scanning for the Study and Engineering of Protein Assemblies
Chemistry–Methods, Volume 6, Issue 8, August 2026.This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger +2 more
wiley +1 more source
Prion shedding is reduced by chronic wasting disease vaccination. [PDF]
PLoS PathogAhmed-Hassan H +10 more
europepmc +1 more source
A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders
Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 357-374, August 2026.Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel +3 more
wiley +1 more source
Strain Traits of Intracranially Administered L-Type Bovine Spongiform Encephalopathy Prions Are not Significantly Modified During Intraspecies Transmission in Cynomolgus Monkeys. [PDF]
Microbiol ImmunolHagiwara K +8 more
europepmc +1 more source
Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review
European Journal of Immunology, Volume 56, Issue 8, August 2026.Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato +2 more
wiley +1 more source
Limited transmission of V180I genetic Creutzfeldt-Jakob disease in knock-in mice models. [PDF]
J Gen VirolTeruya K, Mohri S, Kitamoto T.
europepmc +1 more source
MITF Regulates CFTR Expression to Participate in Myocardial Ischemia–Reperfusion Injury
The Journal of Gene Medicine, Volume 28, Issue 8, August 2026.MITF regulates CFTR expression in MIRI, and disruption of the MITF‐CFTR axis is associated with aggravated injury in cellular and animal models. Restoring CFTR partially mitigates MITF deficiency‐related damage. These findings support the involvement of MITF‐CFTR regulation in MIRI and provide a basis for further mechanistic investigation.
Baoxin Tang +4 more
wiley +1 more source