Results 161 to 170 of about 1,577,570 (335)

Romosozumab and Denosumab Combination Therapy After Denosumab in Postmenopausal Osteoporosis

Arthritis &Rheumatology, EarlyView.
Objective Transition from long‐term denosumab (Dmab) to parathyroid hormone‐analogs or romosozumab (Romo) might expose patients to the risk of the so‐called rebound phenomenon. Adding Romo to Dmab might represent an option in patients experiencing a fracture while on Dmab.
Giovanni Adami, Francesco Pollastri, Angelo Fassio, Filippo Montanari, Anna Piccinelli, Camilla Benini, Emma Pasetto, Carmen Dartizio, Davide Gatti, Maurizio Rossini, Ombretta Viapiana   +10 more
wiley   +1 more source

Pragmatic Clinical Trials—Ready for Prime Time? [PDF]

JAMA Network Open, 2021
Mahmoud, Al Rifai, Dipti, Itchhaporia, Salim S, Virani   +2 more
openaire   +2 more sources

Measuring the Impact: MRI Response of Sacroiliac Joints to TNF Inhibitors in Youth with Axial Disease

Arthritis &Rheumatology, Accepted Article.
Objective To evaluate the timeline for resolution of sacroiliac joint (SIJ) inflammation, changes in structural lesions, and their correlation with patient‐reported outcomes in youth with axial juvenile spondyloarthritis (axJSpA) initiating TNF inhibitor (TNFi).
Timothy G. Brandon, Rui Xiao, Daniel J. Lovell, Edward Oberle, Matthew L. Stoll, Nancy A. Chauvin, Michael L. Francavilla, Walter P. Maksymowych, Pamela F. Weiss   +8 more
wiley   +1 more source

The Rethinking Clinical Trials (REaCT) Program: A Pragmatic Research Strategy to Improve Cancer Care for Patients, Caregivers, and Healthcare Systems

Current Oncology
Cancer care has become increasingly complex, expensive, and inaccessible, with patients often exposed to increased treatment-related harms for marginal benefits.
Marie-France Savard, Mark Clemons, Sharon F. McGee   +2 more
doaj   +1 more source

Eurocentric Bias in Dysmorphology and Medical Genetics Education

American Journal of Medical Genetics Part A, EarlyView.
D' Arcy B. Prendergast, Emma Sullivan, Michael P. Mackley, Hanna Faghfoury   +3 more
wiley   +1 more source

The Effect of Intranasal Niclosamide on Nasal Symptoms in Patients with Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

Arthritis &Rheumatology, EarlyView.
Objective Ear, nose, and throat (ENT) manifestations are common in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). There is an unmet need for drugs to target these manifestations. Granuloma formation is characteristic of proteinase 3 (PR3)–AAV. In a zebrafish model, niclosamide inhibits PR3‐induced granuloma formation.
Benjamin Lim, Wendi Qian, Francis Dowling, Alan Salama, Rona M Smith   +4 more
wiley   +1 more source

Single‐cell level characterization of B cell depletion and repopulation following rituximab in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Augmented reality for teaching undergraduate human anatomy: An educators' perspective

Anatomical Sciences Education, EarlyView.
Abstract The purpose of this study was to explore the perspectives of Australian educators on using augmented reality (AR) as a method for learning human anatomy in the undergraduate health sciences. This will determine the current value of AR and guide future research and development. This prospective qualitative study used a mixed‐methods approach to
Ally Williams, Zhonghua Sun, Mauro Vaccarezza   +2 more
wiley   +1 more source

Comparison of examination performance and test anxiety during bell‐paced and self‐paced gross anatomy laboratory examinations

Anatomical Sciences Education, EarlyView.
Abstract Pacing during anatomy laboratory examinations may influence both student performance and test anxiety. This study compared bell‐paced (BP) and self‐paced (SP) timing structures to assess their impact on students' test performance, test anxiety, and pacing preferences.
Danielle C. Bentley, Angelo Sotto, Peter Lombardi   +2 more
wiley   +1 more source

Information retrieval or document retrieval? Terminological confusions and unrealistic goals in information science, exemplified in relation to generative artificial intelligence

Journal of the Association for Information Science and Technology, EarlyView.
Abstract ChatGPT and related technologies have revived an old issue in information science (IS) concerning information retrieval (IR) versus document retrieval. Since 1950, the term IR has primarily been used as a misnomer for document retrieval. This problematic terminology reflects a desire to go beyond documents and provide, in response to user ...
Birger Hjørland
wiley   +1 more source