Results 171 to 180 of about 6,158,274 (301)

Interaction Between Chronotype and the Timing of Antihypertensive Medication on Cardiovascular Events and Death

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Scott R. Garrison   +30 more
doaj   +1 more source

Unloader Bracing Is a Biomechanically Rational and Clinically Useful Intervention in Selected Patients With Tibiofemoral Joint Cartilage Pathology: A Modified Delphi Consensus Study

open access: yesArthroscopy, EarlyView.
Purpose To establish an international expert consensus on the role of unloader bracing in the management of focal tibiofemoral cartilage lesions using Delphi methodology to inform clinical decision‐making in both nonoperative and operative contexts and identify future research priorities.
Jonathan T. Super   +37 more
wiley   +1 more source

Clean Cut (adaptive, multimodal surgical infection prevention programme) for low‐resource settings: a prospective quality improvement study

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester   +16 more
wiley   +1 more source

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker   +17 more
wiley   +1 more source

Meeting People Where They Are: Strategies for Improving Rural Representation in Clinical Research through Pragmatic Clinical Trials. [PDF]

open access: yesJ Rural Health
Lovejoy TI   +15 more
europepmc   +1 more source

A Pragmatic Trial of a Shared Decision‐Making Intervention to Improve Medication Adherence and Outcomes in Systemic Lupus Erythematosus: The HCQ‐SAFE Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective Hydroxychloroquine (HCQ) nonadherence in systemic lupus erythematosus (SLE) stemming from decision complexities can be improved with shared decision‐making (SDM) tools clarifying benefits and harms. This study aimed to develop and evaluate HCQ‐SAFE, a pictogram‐based SDM tool during SLE visits.
Caroline Packee   +8 more
wiley   +1 more source

The design of embedded pragmatic clinical trials: methodological developments and statistical lessons learned from the first cycle of the NIA IMPACT collaboratory. [PDF]

open access: yesAlzheimers Dement
Travison TG   +9 more
europepmc   +1 more source

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo   +7 more
wiley   +1 more source

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