Results 181 to 190 of about 71,888 (256)

Effectiveness of electronic medical record-based strategies for death and hospital admission endpoint capture in pragmatic clinical trials. [PDF]

J Am Med Inform Assoc
Rahafrooz M, Elbers DC, Gopal JR, Ren J, Chan NH, Yildirim C, Desai AS, Santos AA, Murray K, Havighurst T, Udell JA, Farkouh ME, Cooper L, Gaziano JM, Vardeny O, Mao L, Kim K, Gagnon DR, Solomon SD, Joseph J.   +19 more
europepmc   +1 more source

Evaluating the Impact of Enhanced Stent Visualization on PCI Outcomes in Older Patients With Multivessel Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Optimal stent expansion is a key determinant of long‐term outcomes after PCI. Intravascular imaging provides the most accurate assessment of stent deployment but remains underused, especially in older patients with MI and multivessel disease.
Marta Cocco, Alberto Sarti, Filippo Maria Verardi, Serena Caglioni, Jacopo Farina, Carlo Penzo, Carlo Tumscitz, Matteo Serenelli, Renè Tezze, Anna Cantone, Andrea Erriquez, Gianluca Campo, Simone Biscaglia   +12 more
wiley   +1 more source

Use of Epic^® to facilitate high-quality randomization of emergency department-based pragmatic clinical trials. [PDF]

Clin Trials
Toerper MF, Haukoos J, Hopkins E, Rowan SE, Lyons MS, Galbraith JW, Hsieh YH, White DA, Levin S, Hinson J, Rothman RE, HIV TESTED and DETECT Hep C Trials Investigators.   +11 more
europepmc   +1 more source

Primary Percutaneous Coronary Intervention Guided by High‐Definition Intravascular Ultrasound (The SPECTRUM Study)

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Limited data are available on the use of intravascular ultrasound (IVUS) in patients presenting with ST‐segment elevation myocardial infarction (STEMI). Aims This study aimed to assess the impact of IVUS‐guided primary percutaneous coronary intervention (PCI).
Frederik T. W. Groenland, Annemieke C. Ziedses des Plantes, Tara Neleman, Jurgen M. R. Ligthart, Karen T. Witberg, Rutger‐Jan Nuis, Jeroen M. Wilschut, Roberto Diletti, Wijnand K. den Dekker, Isabella Kardys, Paul Cummins, Karim D. Mahmoud, Nicolas M. Van Mieghem, Joost Daemen   +13 more
wiley   +1 more source

Pragmatic clinical trials as hybrid effectiveness-implementation studies to shrink the evidence-to-practice gap for chronic pain management. [PDF]

Pain Med
Midboe AM, Seal KH, Burgess DJ, Rosen MI, Martino S.   +4 more
europepmc   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Association of Urinary pH With Overall Survival in Patients With Stage IV Cancer: A Single‐Center Retrospective Cohort Study

Cancer Nexus, EarlyView.
ABSTRACT Objective This single‐center retrospective cohort study evaluated whether, among patients with stage IV cancer who participated in a pragmatic “alkalization therapy”—defined as a low potential renal acid load diet plus oral sodium bicarbonate and/or potassium/sodium citrate—urinary pH was associated with long‐term survival.
Shion Kachi, Kazuyuki Suzuki, Reo Hamaguchi, Ryoko Narui, Hiromasa Morikawa, Hiromi Wada   +5 more
wiley   +1 more source

Impact of the COVID-19 pandemic on participants in pragmatic clinical trials for chronic pain: implications for trial outcomes and beyond. [PDF]

Pain Med
Sellinger JJ, Gilstad-Hayden K, Lazar C, Seal K, Purcell N, Burgess DJ, Martino S, Heapy A, Higgins D, Rosen MI.   +9 more
europepmc   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

Clinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples, Shayna R. Killam, Karen E. Brown, Rachel Dalton, Elizabeth Sather, Qiang Chen, Joshua Loveland, Corbin Schwanke, Abdallah F. Elias, Kristin L. Bigos, Erica L. Woodahl   +10 more
wiley   +1 more source