A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report. [PDF]
Clin Case RepABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Tamang S +6 more
europepmc +2 more sources
Return to Spontaneous Circulation in a Patient With Cholinergic Syndrome at the Emergency Department of Buea Regional Hospital, Cameroon. [PDF]
Clin Case RepABSTRACT With the increasing misuse of herbal treatment and pesticides, cases of cholinergic syndrome following herbal treatment or organophosphate poisoning have become increasingly common in our milieu. However, when advanced, mortality is high. We report the successful management of a case involving a 54‐year‐old African female with a known history ...
Nteungue BBK +3 more
europepmc +2 more sources
Kuwait Journal of Science, 2022 The aim of this work was to investigate the inhibition effects of some organophosphate and pyrethroid pesticides on antioxidant enzymes. In addition, oximes were reported by reactivation ability against pesticide inhibited-acetylcholinesterase and we ...
Hatice Paluzar, Ayten Sagiroglu
doaj +1 more source
Organophosphorus Poisoning with Homicidal Intention in a Neonate
Indian Journal of Neonatal Medicine and Research, 2022 Organophosphorus Compounds (OPC) are widely used as pesticides, and poisoning due to OPC is very rare in neonates. A 12-day- old female neonate was admitted with gasping respiration, excessive oral secretions and cold extremities.
Laxman Basany, Roja Aepalapala
doaj +1 more source
FDA-Approved Oximes and Their Significance in Medicinal Chemistry
Pharmaceuticals, 2022 Despite the scientific advancements, organophosphate (OP) poisoning continues to be a major threat to humans, accounting for nearly one million poisoning cases every year leading to at least 20,000 deaths worldwide.
Jyothi Dhuguru +2 more
doaj +1 more source
Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
, 2020 Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core +1 more source
Treatment of Organophosphorus Exposure and Precautions in Using Succinylcholine
Archives of Anesthesia and Critical Care, 2023 Ali Jabbari +3 more
doaj +1 more source
Molecules, 2020 Background: Oximes are used in addition to atropine to treat organophosphate poisoning. However, the efficiency of oximes is still a matter of debate. In vitro experiments suggested than new oximes are more potent than the commercial oximes. However, the
Maya Kayouka +4 more
doaj +1 more source
Pharmacokinetic analysis of pralidoxime after its intramuscular injection alone or in combination with atropine-avizafone in healthy volunteers [PDF]
, 2010 BACKGROUND AND PURPOSE Treatment of organophosphate poisoning with pralidoxime needs to be improved. Here we have studied the pharmacokinetics of pralidoxime after its intramuscular injection alone or in combination with avizafone and atropine using an ...
A. Turcant +7 more
core +3 more sources
Pharmacological Blockade of the Calcium Plateau Provides Neuroprotection Following Organophosphate Paraoxon Induced Status Epilepticus in Rats [PDF]
, 2016 Organophosphate (OP) compounds which include nerve agents and pesticides are considered chemical threat agents. Currently approved antidotes are crucial in limiting OP mediated acute mortality.
Ajdacic-Gross +43 more
core +2 more sources