Results 41 to 50 of about 821 (107)

A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Sujan Tamang   +6 more
wiley   +1 more source

Exposure the Hazardous Potential of Quinalphos: An In‐Depth Analysis for Environmental and Biological Effects on Human Health

open access: yesIET Systems Biology, Volume 20, Issue 1, January/December 2026.
This study elucidates pesticide docking onto proteins encoded by differentially expressed genes, revealing interaction networks involving chemicals, genes, proteins, drugs and diseases. It highlights structural insights, regulatory pathways and potential therapeutic or environmental implications, providing a comprehensive understanding of the ...
Jyoti Kant Choudhari   +4 more
wiley   +1 more source

1,3–Bis(2–hydroxyiminomethylpyridinium) Propane as the Potential Reactivator of the Acetylcholinesterase Inhibited by Nerve Agents

open access: yesActa Medica, 2004
The oxime K005 [1,3–bis(2–hydroxyiminomethylpyridinium) propane dibromide] for the reactivation of the enzyme acetylcholinesterase (AChE) inhibited by cyclosarin and VX was tested.
Kamil Kuča, Vlastimil Dohnal
doaj   +1 more source

Cardiac damage in acute organophosphate poisoning in rats: Effects of atropine and pralidoxime{star, open}

open access: yes, 2009
Anticholinesterase poisoning is an important health problem in our country, and a complete understanding of its underlying mechanisms is essential for the emergency physician. Thus, we aimed to investigate the cardiac biochemical parameters and mortality
Demiryurek, Abdullah T.   +5 more
core   +1 more source

Reactivation Potency of New Group of Acetylcholinesterase Reactivators and Their Comparison with Currently Available Oximes

open access: yesActa Medica, 2006
In this work, in vitro potency of novel serie of monoquaternary pyridinium oximes to reactivate cyclosarin-inhibited acetylcholinesterase (AChE) was tested.
Kamil Kuča, Jan Pícha, Daniel Jun
doaj   +1 more source

Intermediate Syndrome After Organophosphate Poisoning: Clinical Course and a Case of Delayed Neuromuscular Dysfunction

open access: yesCase Reports in Critical Care, Volume 2026, Issue 1, 2026.
Intermediate syndrome (IMS) is a delayed neuromuscular complication of organophosphate poisoning, typically occurring 24–96 h postexposure and often leading to respiratory failure. The author reports a 39‐year‐old male who ingested 40% chlorpyrifos and developed IMS on Day 4 post‐ingestion, presenting with proximal muscle weakness, neck flexor ...
Gudisa Bereda, Lipi Buch
wiley   +1 more source

Return to Spontaneous Circulation in a Patient With Cholinergic Syndrome at the Emergency Department of Buea Regional Hospital, Cameroon

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT With the increasing misuse of herbal treatment and pesticides, cases of cholinergic syndrome following herbal treatment or organophosphate poisoning have become increasingly common in our milieu. However, when advanced, mortality is high. We report the successful management of a case involving a 54‐year‐old African female with a known history ...
Bertolt Brecht Kouam Nteungue   +3 more
wiley   +1 more source

Preformulation Studies of Pralidoxime Chloride for Formulation Development of Microspheres [PDF]

open access: yes, 2019
Microspheres are one of the novel drug delivery system which possess several applications and are made up of assorted polymers. Microspheres can be defined as solid, approximately spherical particles ranging in size from 1 to 1000 μm range in diameter ...
Jain, Suman   +2 more
core   +1 more source

The role of plasmapheresis in organophosphate poisoning: Case reports of three pediatric patients

open access: yesThe Turkish Journal of Pediatrics, 2017
The aim of the study was to assess the impact of plasmapheresis treatment in the management of three pediatric patients with organophosphate poisoning who did not respond to standard treatment.
Ufuk Yükselmiş   +4 more
doaj   +1 more source

Perampanel as a second‐line therapy to midazolam reduces soman‐induced status epilepticus and neurodegeneration in rats

open access: yesEpilepsia Open, Volume 10, Issue 4, Page 1187-1198, August 2025.
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier   +8 more
wiley   +1 more source

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