Results 41 to 50 of about 821 (107)
ABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Sujan Tamang +6 more
wiley +1 more source
This study elucidates pesticide docking onto proteins encoded by differentially expressed genes, revealing interaction networks involving chemicals, genes, proteins, drugs and diseases. It highlights structural insights, regulatory pathways and potential therapeutic or environmental implications, providing a comprehensive understanding of the ...
Jyoti Kant Choudhari +4 more
wiley +1 more source
The oxime K005 [1,3–bis(2–hydroxyiminomethylpyridinium) propane dibromide] for the reactivation of the enzyme acetylcholinesterase (AChE) inhibited by cyclosarin and VX was tested.
Kamil Kuča, Vlastimil Dohnal
doaj +1 more source
Anticholinesterase poisoning is an important health problem in our country, and a complete understanding of its underlying mechanisms is essential for the emergency physician. Thus, we aimed to investigate the cardiac biochemical parameters and mortality
Demiryurek, Abdullah T. +5 more
core +1 more source
In this work, in vitro potency of novel serie of monoquaternary pyridinium oximes to reactivate cyclosarin-inhibited acetylcholinesterase (AChE) was tested.
Kamil Kuča, Jan Pícha, Daniel Jun
doaj +1 more source
Intermediate syndrome (IMS) is a delayed neuromuscular complication of organophosphate poisoning, typically occurring 24–96 h postexposure and often leading to respiratory failure. The author reports a 39‐year‐old male who ingested 40% chlorpyrifos and developed IMS on Day 4 post‐ingestion, presenting with proximal muscle weakness, neck flexor ...
Gudisa Bereda, Lipi Buch
wiley +1 more source
ABSTRACT With the increasing misuse of herbal treatment and pesticides, cases of cholinergic syndrome following herbal treatment or organophosphate poisoning have become increasingly common in our milieu. However, when advanced, mortality is high. We report the successful management of a case involving a 54‐year‐old African female with a known history ...
Bertolt Brecht Kouam Nteungue +3 more
wiley +1 more source
Preformulation Studies of Pralidoxime Chloride for Formulation Development of Microspheres [PDF]
Microspheres are one of the novel drug delivery system which possess several applications and are made up of assorted polymers. Microspheres can be defined as solid, approximately spherical particles ranging in size from 1 to 1000 μm range in diameter ...
Jain, Suman +2 more
core +1 more source
The role of plasmapheresis in organophosphate poisoning: Case reports of three pediatric patients
The aim of the study was to assess the impact of plasmapheresis treatment in the management of three pediatric patients with organophosphate poisoning who did not respond to standard treatment.
Ufuk Yükselmiş +4 more
doaj +1 more source
Abstract Objective A benzodiazepine (diazepam or midazolam) is one of the current standards of care therapies to effectively terminate organophosphorus nerve agent‐induced status epilepticus when administered shortly after onset. Preclinical studies showed that benzodiazepines were less effective in stopping status epilepticus when treatment was ...
Hailey G. Steier +8 more
wiley +1 more source

