Kuwait Journal of Science, 2022 The aim of this work was to investigate the inhibition effects of some organophosphate and pyrethroid pesticides on antioxidant enzymes. In addition, oximes were reported by reactivation ability against pesticide inhibited-acetylcholinesterase and we ...
Hatice Paluzar, Ayten Sagiroglu
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Organophosphorus Poisoning with Homicidal Intention in a Neonate
Indian Journal of Neonatal Medicine and Research, 2022 Organophosphorus Compounds (OPC) are widely used as pesticides, and poisoning due to OPC is very rare in neonates. A 12-day- old female neonate was admitted with gasping respiration, excessive oral secretions and cold extremities.
Laxman Basany, Roja Aepalapala
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Return to Spontaneous Circulation in a Patient With Cholinergic Syndrome at the Emergency Department of Buea Regional Hospital, Cameroon. [PDF]
Clin Case RepABSTRACT With the increasing misuse of herbal treatment and pesticides, cases of cholinergic syndrome following herbal treatment or organophosphate poisoning have become increasingly common in our milieu. However, when advanced, mortality is high. We report the successful management of a case involving a 54‐year‐old African female with a known history ...
Nteungue BBK +3 more
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FDA-Approved Oximes and Their Significance in Medicinal Chemistry
Pharmaceuticals, 2022 Despite the scientific advancements, organophosphate (OP) poisoning continues to be a major threat to humans, accounting for nearly one million poisoning cases every year leading to at least 20,000 deaths worldwide.
Jyothi Dhuguru +2 more
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Treatment of Organophosphorus Exposure and Precautions in Using Succinylcholine
Archives of Anesthesia and Critical Care, 2023 Ali Jabbari +3 more
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Molecules, 2020 Background: Oximes are used in addition to atropine to treat organophosphate poisoning. However, the efficiency of oximes is still a matter of debate. In vitro experiments suggested than new oximes are more potent than the commercial oximes. However, the
Maya Kayouka +4 more
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From Mechanisms to Materials: Oximate Reactivity and Emerging Strategies for Organophosphate Detoxification. [PDF]
ChemphyschemThe development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Rodríguez-Dafonte P.
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Effectiveness of Fresh Frozen Plasma in Management of Acute Organophosphate Intoxicated Patients: An Updated Systematic Review and Meta-Analysis [PDF]
Asia Pacific Journal of Medical Toxicology, 2019 Background:Organophosphate (OP) poisoning is still a major health concern in both developed and developing countries. The standard treatment approaches of (OP) poisoning are not always available as well so they may show a limited success rate.
Ola Nafea +4 more
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Pralidoxime for organophosphate poisoning
The Lancet, 2006 From their randomised trial, Kirti Pawar and colleagues report in today's Lancet on two pralidoxime-dosing schemes in 200 patients who had moderately severe self-poisoning with organophosphorus insecticide.1 After a 2-g loading dose over 30 min, half received a high-dose regimen of 1 g/h pralidoxime iodide for 48 h. The other half received a lower dose:
Eyer, Peter, Buckley, Nicholas
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Contributing Factors for Morbidity and Mortality in Patients with Organophosphate Poisoning on Mechanical Ventilation: A Retrospective Study in a Teaching Hospital [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: One of the most common causes of poisoning in agricultural based developing countries like India is due to Organophosphorus (OP) compound.
Gurulingappa Patil +2 more
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