Computational Design, Molecular Docking Study and Toxicity Prediction of Some Novel Pralidoxime Derivatives as reactivators of acetyl cholinesterase enzyme [PDF]
Journal of Advanced Biomedical Sciences, 2019 Background & Objective: oximes as Acetylcholinesterase (AChE) reactivators were developed for the treatment of organophosphate compounds (OPCs) intoxication.
abozar roeintan
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Acta Medica, 2005 1. The efficacy of the oxime HLö-7 and currently used oximes (pralidoxime, obidoxime, HI-6) to reactivate acetylcholinesterase inhibited by various nerve agents (sarin, tabun, cyclosarin, VX) was tested by in vitro methods. 2. Both H oximes (HLö-7, HI-6)
Kamil Kuča +4 more
doaj +2 more sources
Effectiveness of High Dose Pralidoxime for Treatment of Organophosphate Poisoning [PDF]
Asia Pacific Journal of Medical Toxicology, 2014 Background: For effective treatment of organophosphate (OP) poisoning, development of a standardized protocol with flexible dose regimen for atropine and pralidoxime is an essential step.
Pham Due
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, 1998 It is shown that a silver indicator electrode can be used in the potentiometric titration of pralidoxime chloride [2-pyridinealdoxime methochloride (PAM-2)] with palladium(II) chloride and silver nitrate solutions.
Rajković, MB +2 more
core +6 more sources
Antidote for organophosphate insecticide poisoning: atropine and pralidoxime [PDF]
, 2013 Acute organophosphate (OP) poisoning produces cholinergic symptoms resulting from the inhibition of cholinesterase, and the overstimulation of muscarinic and nicotinic receptors in the synapses.
정성필
core +1 more source
Effectiveness of Fresh Frozen Plasma in Management of Acute Organophosphate Intoxicated Patients: An Updated Systematic Review and Meta-Analysis [PDF]
Asia Pacific Journal of Medical Toxicology, 2019 Background:Organophosphate (OP) poisoning is still a major health concern in both developed and developing countries. The standard treatment approaches of (OP) poisoning are not always available as well so they may show a limited success rate.
Ola Nafea +4 more
doaj +1 more source
Contributing Factors for Morbidity and Mortality in Patients with Organophosphate Poisoning on Mechanical Ventilation: A Retrospective Study in a Teaching Hospital [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: One of the most common causes of poisoning in agricultural based developing countries like India is due to Organophosphorus (OP) compound.
Gurulingappa Patil +2 more
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International Journal of Medical Toxicology and Forensic Medicine, 2022 Background: Organophosphates are among the most common causes of poisoning worldwide—responsible for 3 million poisoning and 200000 deaths every year. Nearly 15% of people who are poisoned die.
Mitra Rahimi +3 more
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Acta Medica, 2021 Aim: The comparison of neuroprotective and central reactivating effects of the oxime K870 in combination with atropine with the efficacy of standard antidotal treatment in tabun-poisoned rats.
Jiří Kassa +5 more
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Surgical Treatment for Hemorrhagic Infarction of Small Intestine Caused by Organophosphate Poisoning
Clinical Case Reports, Volume 14, Issue 9, September 2026.ABSTRACT Acute organophosphorus pesticide poisoning (AOPP) may cause intestinal infarction via intra‐abdominal hypertension (IAH) and non‐occlusive mesenteric ischemia (NOMI). Although this complication carries high mortality, early laparotomy, resection of necrotic bowel, and comprehensive therapy can improve survival, as supported by our successfully
Yi‐Yun Sun +5 more
wiley +1 more source