Results 11 to 20 of about 821 (107)
Pralidoxime in organophosphorus poisoning
Journal of Nepal Medical Association, 2010 INTRODUCTION: Pralidoxime are enzyme reactivator that are known to reactivate the phosphorylated acetylcholinesterase by binding to the organophosphorus molecule.
N R Simkhada, KK Kafle, PN Prasad
doaj +2 more sources
Saudi Journal of Anaesthesia, 2015 Background: Organophosphorus poisoning (OPP) is a major global public health problem. Pralidoxime has been used in a complimentary role to atropine for the management of OPP.
Sumaya Syed +5 more
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A Study on Two Dose Regimens of Pralidoxime in the Management of Organophosphate Poisoning [PDF]
Asia Pacific Journal of Medical Toxicology, 2013 Background: The role and proper dose of pralidoxime in the treatment of Organophosphorus (OP) compounds poisoning is an unresolved issue .This study was designed to compare the regimen recommended by the World Health Organization (WHO) with the commonly ...
Mahadevaiah Mahesh +2 more
doaj +1 more source
The Experimental Oxime K027—A Promising Protector From Organophosphate Pesticide Poisoning. A Review Comparing K027, K048, Pralidoxime, and Obidoxime [PDF]
Frontiers in Neuroscience, 2019 Poisoning with organophosphorus compounds (OPCs) is a major problem worldwide. Standard therapy with atropine and established oxime-type enzyme reactivators (pralidoxime, obidoxime) is unsatisfactory.
Dietrich E. Lorke +2 more
doaj +4 more sources
Organophosphate Poisoning: Insights From a Case Report of Acute Cholinergic Syndrome
Clinical Case ReportsOrganophosphate (OP) pesticides are widely used in agriculture and can cause acute cholinergic toxicity by inhibiting the enzyme acetylcholinesterase, leading to an accumulation of acetylcholine.
Gudisa Bereda
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SeparationsPralidoxime chloride, a highly hydrophilic antidote, cannot be effectively separated by reverse-phase high-performance liquid chromatography (RP-HPLC), unless the mobile-phase composition is varied.
Bohyun Shin +10 more
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Comparative Study of Continuous Pralidoxime Infusion versus Intermittent Dosing: Application of High-Performance Liquid Chromatography Method on Serum of Organophosphate Poisoned Patients [PDF]
Asia Pacific Journal of Medical Toxicology, 2013 Background: The effective therapeutic dose of pralidoxime methylsulphate for organophosphate (OP) poisoning is necessary to be clarified. This study was designed to comparatively assess the blood level of pralidoxime (BPL) and clinical outcomes in OP ...
Girish Thunga +7 more
doaj +1 more source
Pralidoxime and pesticide poisoning: A question of severity?
Biomedical Journal, 2016 In this issue of the Biomedical Journal, we highlight new data supporting the use of pralidoxime in the treatment of cases of organophosphate poisoning, which also suggest that WHO treatment guidelines should be updated.
Emma Louise Walton
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Clinical Case ReportsOrganophosphate poisoning can precipitate acute atrial fibrillation even in previously healthy individuals. This first documented case from Pakistan of Malathion‐induced atrial fibrillation emphasizes the need for early recognition, continuous cardiac ...
Qurat ul Ain +3 more
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Scientific Reports, 2022 Pesticides account for hundreds of millions of cases of acute poisoning worldwide each year, with organophosphates (OPs) being responsible for the majority of all pesticide-related deaths.
Sarah Piel +13 more
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