Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial. [PDF]
PLoS Medicine, 2009 BackgroundPoisoning with organophosphorus (OP) insecticides is a major global public health problem, causing an estimated 200,000 deaths each year.
Michael Eddleston +14 more
doaj +2 more sources
Saudi Journal of Anaesthesia, 2015 Background: Organophosphorus poisoning (OPP) is a major global public health problem. Pralidoxime has been used in a complimentary role to atropine for the management of OPP.
Sumaya Syed +5 more
doaj +2 more sources
A Study on Two Dose Regimens of Pralidoxime in the Management of Organophosphate Poisoning [PDF]
Asia Pacific Journal of Medical Toxicology, 2013 Background: The role and proper dose of pralidoxime in the treatment of Organophosphorus (OP) compounds poisoning is an unresolved issue .This study was designed to compare the regimen recommended by the World Health Organization (WHO) with the commonly ...
Mahadevaiah Mahesh +2 more
doaj +1 more source
SeparationsPralidoxime chloride, a highly hydrophilic antidote, cannot be effectively separated by reverse-phase high-performance liquid chromatography (RP-HPLC), unless the mobile-phase composition is varied.
Bohyun Shin +10 more
doaj +2 more sources
Comparative Study of Continuous Pralidoxime Infusion versus Intermittent Dosing: Application of High-Performance Liquid Chromatography Method on Serum of Organophosphate Poisoned Patients [PDF]
Asia Pacific Journal of Medical Toxicology, 2013 Background: The effective therapeutic dose of pralidoxime methylsulphate for organophosphate (OP) poisoning is necessary to be clarified. This study was designed to comparatively assess the blood level of pralidoxime (BPL) and clinical outcomes in OP ...
Girish Thunga +7 more
doaj +1 more source
The Experimental Oxime K027—A Promising Protector From Organophosphate Pesticide Poisoning. A Review Comparing K027, K048, Pralidoxime, and Obidoxime [PDF]
Frontiers in Neuroscience, 2019 Poisoning with organophosphorus compounds (OPCs) is a major problem worldwide. Standard therapy with atropine and established oxime-type enzyme reactivators (pralidoxime, obidoxime) is unsatisfactory.
Dietrich E. Lorke +2 more
doaj +4 more sources
Pralidoxime and pesticide poisoning: A question of severity?
Biomedical Journal, 2016 In this issue of the Biomedical Journal, we highlight new data supporting the use of pralidoxime in the treatment of cases of organophosphate poisoning, which also suggest that WHO treatment guidelines should be updated.
Emma Louise Walton
doaj +2 more sources
A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report. [PDF]
Clin Case RepABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Tamang S +6 more
europepmc +2 more sources
Effectiveness of High Dose Pralidoxime for Treatment of Organophosphate Poisoning [PDF]
Asia Pacific Journal of Medical Toxicology, 2014 Background: For effective treatment of organophosphate (OP) poisoning, development of a standardized protocol with flexible dose regimen for atropine and pralidoxime is an essential step.
Pham Due
doaj +1 more source
, 1998 It is shown that a silver indicator electrode can be used in the potentiometric titration of pralidoxime chloride [2-pyridinealdoxime methochloride (PAM-2)] with palladium(II) chloride and silver nitrate solutions.
Rajković, MB +4 more
core +7 more sources