Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial.
PLoS Medicine, 2009 BackgroundPoisoning with organophosphorus (OP) insecticides is a major global public health problem, causing an estimated 200,000 deaths each year.
Michael Eddleston +14 more
doaj +1 more source
Atropine Use in Children After Nerve Gas Exposure [PDF]
, 2004 Following the FDA's approval of a pediatric dosage Atropen®, the Pediatric Expert Advisory Panel was asked to review the existing guidelines and recommendations regarding the treatment of children exposed to nerve agents and the Mark-1 Kit; review the ...
National Center for Disaster Preparedness
core +2 more sources
Saudi Journal of Anaesthesia, 2015 Background: Organophosphorus poisoning (OPP) is a major global public health problem. Pralidoxime has been used in a complimentary role to atropine for the management of OPP.
Sumaya Syed +5 more
doaj +1 more source
Pediatric Emergency Preparedness for Natural Disasters, Terrorism, and Public Health Emergencies: A National Consensus Conference: 2009 Update [PDF]
, 2009 This is the third consensus document in an ongoing process to convene experts from the multiple disciplines that are involved in the planning for children affected by ...
Garrett, Andrew L., Redlener, Irwin E.
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Effectiveness of Fresh Frozen Plasma in Management of Acute Organophosphate Intoxicated Patients: An Updated Systematic Review and Meta-Analysis [PDF]
Asia Pacific Journal of Medical Toxicology, 2019 Background:Organophosphate (OP) poisoning is still a major health concern in both developed and developing countries. The standard treatment approaches of (OP) poisoning are not always available as well so they may show a limited success rate.
Ola Nafea +4 more
doaj +1 more source
High-performance liquid chromatography coupled with electrospray tandem mass spectrometry (LC/MS/MS) method for the simultaneous determination of diazepam, atropine and pralidoxime in human plasma [PDF]
, 2008 A high-performance liquid chromatography coupled with electrospray tandem mass spectrometry (LC/MS/MS) procedure for the simultaneous determination of diazepam from avizafone, atropine and pralidoxime in human plasma is described.
A. Cailleux +7 more
core +2 more sources
Contributing Factors for Morbidity and Mortality in Patients with Organophosphate Poisoning on Mechanical Ventilation: A Retrospective Study in a Teaching Hospital [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: One of the most common causes of poisoning in agricultural based developing countries like India is due to Organophosphorus (OP) compound.
Gurulingappa Patil +2 more
doaj +1 more source
OpdA, a bacterial organophosphorus hydrolase, prevents lethality in rats after poisoning with highly toxic organophosphorus pesticides [PDF]
, 2008 Organophosphorus (OP) pesticides poison more than 3,000,000 people every year in the developing world, mostly through intentional self-poisoning. Advances in medical therapy for OP poisoning have lagged, and current treatment is not highly effective with
Adie +26 more
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Comparative Study of Continuous Pralidoxime Infusion versus Intermittent Dosing: Application of High-Performance Liquid Chromatography Method on Serum of Organophosphate Poisoned Patients [PDF]
Asia Pacific Journal of Medical Toxicology, 2013 Background: The effective therapeutic dose of pralidoxime methylsulphate for organophosphate (OP) poisoning is necessary to be clarified. This study was designed to comparatively assess the blood level of pralidoxime (BPL) and clinical outcomes in OP ...
Girish Thunga +7 more
doaj
Predicting outcome using butyrylcholinesterase activity in organophosphorus pesticide self-poisoning [PDF]
, 2008 Background: The usefulness of a low butyrylcholinesterase (BuChE) activity on admission for predicting severity in acute organophosphorus (OP) insecticide poisoning has long been debated. Previous studies have been confounded by the inclusion of multiple
Buckley, N. A. +4 more
core +1 more source