Results 41 to 50 of about 3,544 (200)

Prevalence of Delayed Neuropathy and Intermediate Syndrome in Acute Organophosphorus Poisoning: A Cross-sectional Toxicological/Clinical Study

International Journal of Medical Toxicology and Forensic Medicine, 2022
Background: Organophosphates are among the most common causes of poisoning worldwide—responsible for 3 million poisoning and 200000 deaths every year. Nearly 15% of people who are poisoned die.
Mitra Rahimi, Rezvan Kefayati, Shahin Shadnia, Peyman Erfan Talab Evini   +3 more
doaj   +1 more source

What Target Pralidoxime Concentration? [PDF]

Journal of Toxicology: Clinical Toxicology, 1997
(1997). What Target Pralidoxime Concentration? Journal of Toxicology: Clinical Toxicology: Vol. 35, No. 2, pp. 227-228.
Andrew Dawson, Nick Buckley, Ian Whyte
openaire   +1 more source

Intoxication aiguë sévère par les pesticides organophosphorés: à propos de 28 cas [PDF]

, 2011
Les pesticides organophosphorés (POP) sont des pesticides organiques de synthèse, largement utilisés en agriculture essentiellement comme insecticide, nemacide ou acaricide.
Abderrahim Elbouazzaoui, Ali Derkaoui, Hicham Sbai, Mohammed Khatouf, Mustapha Harrandou, Nabil Kanjaa, Noufel Elhouari, Sanae Achour, Smael Labib   +8 more
core   +3 more sources

Self injection of Dichlorvos, an Organophosphorus Compound [PDF]

, 2008
We report two patients who injected themselves a strong organophosphate compound, dichlorvas, and showed the typical clinical picture of organophosphate intoxication. There are very few case reports of parenteral organophosphorous poisoning.
DM, Mahesh, Gupta, Dalip, Kaushal, Satinder Singh, Raina, Sujeet, Sood, Vivek   +4 more
core   +1 more source

Vibrational analysis of 1-methyl-pyridinium-2-aldoxime- and 1-methyl-pyridinium-4-aldoxime chloride [PDF]

, 2011
Pyrimidinium aldoximes are administered in cases of acute organophosphate poisoning. Since questions regarding their morphology and active conformation in the solid state are still open, an effort was made to establish correspondence between their ...
Foretić, Blaženka, Gamulin, Ozren, Mohaček Grošev, Vlasta   +2 more
core   +1 more source

Intermediate Syndrome After Organophosphate Poisoning: Clinical Course and a Case of Delayed Neuromuscular Dysfunction

Case Reports in Critical Care, Volume 2026, Issue 1, 2026.
Intermediate syndrome (IMS) is a delayed neuromuscular complication of organophosphate poisoning, typically occurring 24–96 h postexposure and often leading to respiratory failure. The author reports a 39‐year‐old male who ingested 40% chlorpyrifos and developed IMS on Day 4 post‐ingestion, presenting with proximal muscle weakness, neck flexor ...
Gudisa Bereda, Lipi Buch
wiley   +1 more source

Succinate prodrugs in combination with atropine and pralidoxime protect cerebral mitochondrial function in a rodent model of acute organophosphate poisoning

Scientific Reports, 2022
Pesticides account for hundreds of millions of cases of acute poisoning worldwide each year, with organophosphates (OPs) being responsible for the majority of all pesticide-related deaths.
Sarah Piel, Joanna I. Janowska, J. Laurenson Ward, Meagan J. McManus, Joshua S. Jose, Jonathan Starr, Malkah Sheldon, Carly L. Clayman, Eskil Elmér, Magnus J. Hansson, David H. Jang, Michael Karlsson, Johannes K. Ehinger, Todd J. Kilbaugh   +13 more
doaj   +1 more source

Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity [PDF]

, 2014
Organophosphate (OP) compounds, including paraoxon (POX), are similar to nerve agents such as sarin. There is a growing concern that OP agents could be weaponized to cause mass civilian causalities.
DeLorenzo, Robert J., Deshpande, Laxmikant Sudhir, Huang, Beverly, Phillips, Kristin   +3 more
core   +2 more sources

Antidote administration in mice exposed to sarin resulted in brainwave stabilization without cognitive protection

Neuroscience Research
Resurgence of sarin use in the Syrian conflict demonstrates that chemical weapons are a vivid threat. Like other organophosphate compounds, sarin inhibits acetylcholinesterase resulting in cholinergic crisis.
Mélanie Lagadec, Pauline Thiebot, Isabelle Malissin, Alexandre Champault, Julie Somkhit, Julie Knoertzer, Assia Belkebir, Bruno Megarbane, Karine Thibault, Gregory Dal Bo   +9 more
doaj   +1 more source

Computational Design, Molecular Docking Study and Toxicity Prediction of Some Novel Pralidoxime Derivatives as reactivators of acetyl cholinesterase enzyme [PDF]

Journal of Advanced Biomedical Sciences, 2019
Background & Objective: oximes as Acetylcholinesterase (AChE) reactivators were developed for the treatment of organophosphate compounds (OPCs) intoxication.
abozar roeintan
doaj