Results 61 to 70 of about 3,544 (200)
Cu‐Based Nanomaterials for Oxime Electrosynthesis: Advances, Challenges, and Perspectives
cMat, Volume 2, Issue 1, March 2025.ABSTRACT Cu‐based nanomaterials have demonstrated great potential for catalyzing the electrosynthesis of oxime compounds, a type of organonitrogen molecule that finds versatile applications in the pharmaceutical industry, medicine production, chemical feedstocks, and other fields.
Xun‐Ying Liu +5 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 3, March 2025.Acute poisoning with the organophosphate, soman, triggers status epilepticus that rapidly becomes refractory to standard of care treatment with midazolam (MDZ). Combined treatment with MDZ and allopregnanolone (ALLO) significantly suppresses seizure activity, which is associated with attenuated neurodegeneration and neuroinflammation.
Peter M. Andrew +10 more
wiley +1 more source
ChemPlusChem, Volume 89, Issue 8, August 2024.Fast and reliable detection of Nerve Agents (NAs) in the environment still represent an urgent need in emergency situation. The development of practical, portable sensing technology, accessible to non‐specialized operators, performing fast detection of NAs, still represents a challenge.
Roberta Puglisi +3 more
wiley +1 more source
The role of plasmapheresis in organophosphate poisoning: Case reports of three pediatric patients
The Turkish Journal of Pediatrics, 2017 The aim of the study was to assess the impact of plasmapheresis treatment in the management of three pediatric patients with organophosphate poisoning who did not respond to standard treatment.
Ufuk Yükselmiş +4 more
doaj +1 more source
Effect of extract of Varthemia persica DC on whole blood acetylcholinesterase activity in rats [PDF]
, 2016 Varthemia persica DC. is an aromatic plant, from the Asteraceae family, wildly growing in the central provinces of Iran. Sesquiterpene lactones that are found in Varthemia species have protective effect against organophosphates toxicity. This study aimed
Asadi-Samani, Majid. +3 more
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Oxime Derivatives: A Valid Pharmacophore in Medicinal Chemistry
ChemistrySelect, Volume 9, Issue 27, July 18, 2024.Oximes are considered as versatile pharmacophores in discovery new class of medicinally active agents. The incorporation of hydroxylamine‐containing moieties to the carbonyl compounds can generate variety oximes. The current review focused on 49 reports, describing about various activities, including antimicrobial, anticancer, anti‐inflammatory ...
Namitha Chandran +13 more
wiley +1 more source
Pralidoxime and pesticide poisoning: A question of severity?
Biomedical Journal, 2016 In this issue of the Biomedical Journal, we highlight new data supporting the use of pralidoxime in the treatment of cases of organophosphate poisoning, which also suggest that WHO treatment guidelines should be updated.
Emma Louise Walton
doaj +1 more source
Biomolecules, 2020 (1) Background: Human exposure to organophosphorus compounds employed as pesticides or as chemical warfare agents induces deleterious effects due to cholinesterase inhibition. One therapeutic approach is the reactivation of inhibited acetylcholinesterase
André-Guilhem Calas +18 more
doaj +1 more source
Recent Developments in the Ruthenium‐Catalyzed Azide Alkyne Cycloaddition (RuAAC) Reaction
European Journal of Organic Chemistry, Volume 27, Issue 25, July 1, 2024.The Ruthenium‐Catalyzed Azide Alkyne Cycloaddition (RuAAC) provides selective access to both 1,5‐disubstituted and 1,4,5‐trisubstituted 1,2,3‐triazoles in a single step from alkynes and organic azides. The reaction has quickly made its mark in a wide range of areas, spanning from peptidomimetics and antibacterials, to the preparation of functionalized ...
Flavia Ferrara +2 more
wiley +1 more source
Acta Medica, 2005 1. The efficacy of the oxime HLö-7 and currently used oximes (pralidoxime, obidoxime, HI-6) to reactivate acetylcholinesterase inhibited by various nerve agents (sarin, tabun, cyclosarin, VX) was tested by in vitro methods. 2. Both H oximes (HLö-7, HI-6)
Kamil Kuča +4 more
doaj +1 more source