Results 11 to 20 of about 3,627,712 (198)

A Whiff of Garlic, a Turn of Fate: Recognizing Organophosphorus Poisoning Amid Diagnostic Uncertainty: A Case Report. [PDF]

Clin Case Rep
ABSTRACT OP compounds, commonly used as pesticides, are readily available over the counter and frequently implicated in intentional poisoning. We report a case of a 43‐year‐old male with OP poisoning initially misdiagnosed as alcohol intoxication. He was intubated in the emergency department on arrival due to a low Glasgow Coma Scale (GCS) of 6/15 and ...
Tamang S, Amatya BR, Neupane S, Neupane SC, Panta C, Pal A, Shrestha D.   +6 more
europepmc   +2 more sources

Atrial Fibrillation Following Acute Malathion Ingestion: A Rare Cardiac Manifestation of Organophosphate Poisoning. [PDF]

Clin Case Rep
ABSTRACT Organophosphate poisoning can precipitate acute atrial fibrillation even in previously healthy individuals. This first documented case from Pakistan of Malathion‐induced atrial fibrillation emphasizes the need for early recognition, continuous cardiac monitoring, prompt atropine and pralidoxime therapy, electrolyte correction, and timely ...
Ain QU, Hamza M, Rehman A, Omarzai RG.
europepmc   +2 more sources

Organophosphate Poisoning: Insights From a Case Report of Acute Cholinergic Syndrome. [PDF]

Clin Case Rep
ABSTRACT Organophosphate (OP) pesticides are widely used in agriculture and can cause acute cholinergic toxicity by inhibiting the enzyme acetylcholinesterase, leading to an accumulation of acetylcholine. A 45‐year‐old male plumber was admitted to the emergency department 4 h after ingesting an unknown quantity of a 50% emulsifiable concentration of ...
Bereda G.
europepmc   +2 more sources

Return to Spontaneous Circulation in a Patient With Cholinergic Syndrome at the Emergency Department of Buea Regional Hospital, Cameroon. [PDF]

Clin Case Rep
ABSTRACT With the increasing misuse of herbal treatment and pesticides, cases of cholinergic syndrome following herbal treatment or organophosphate poisoning have become increasingly common in our milieu. However, when advanced, mortality is high. We report the successful management of a case involving a 54‐year‐old African female with a known history ...
Nteungue BBK, Nyuydzefon B, Kouomogne BAN, Siysi VV.   +3 more
europepmc   +2 more sources

Case Report: Organophosphorus Section Poisoning-Induced Intermediate Extrapyramidal Syndrome [PDF]

Journal of Clinical and Diagnostic Research, 2023
Organophosphate (OP) compounds are one of the most common agents used for deliberate self-harm in developing countries, including India. OP compounds inhibit the enzyme acetylcholinesterase, which is responsible for hydrolysing the neurotransmitter ...
Puneeth M Reddy, Karthik CH Reddy
doaj   +1 more source

A comparative study of atropine and atropine plus pralidoxime in the management of organo-phosphorous poisoning

International Journal of Advances in Medicine, 2023
Background: Poisoning with organophosphorus compounds (OP) is a common problem throughout the world particularly in developing countries.
S. Baruah, J. K. Das, Imdadul Hossain, N. B. Singh   +3 more
semanticscholar   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva, Wellington V. dos Santos, Vinicius C. V. da Rocha, Joyce S. F. D. de Almeida, Leandro B. Bernardo, Taynara Carvalho-Silva, Cintia N. Ferreira, Angelo A. T. da Silva, Alessandro B. C. Simas, Eugenie Nepovimova, Kamil Kuča, Tanos C. C. França, Samir F. de A. Cavalcante   +14 more
doaj   +1 more source

Organophosphorus Poisoning with Homicidal Intention in a Neonate

Indian Journal of Neonatal Medicine and Research, 2022
Organophosphorus Compounds (OPC) are widely used as pesticides, and poisoning due to OPC is very rare in neonates. A 12-day- old female neonate was admitted with gasping respiration, excessive oral secretions and cold extremities.
Laxman Basany, Roja Aepalapala
doaj   +1 more source

The Efficacy of Pralidoxime in the Treatment of Organophosphate Poisoning in Humans: A Systematic Review and Meta-analysis of Randomized Trials

Cureus, 2020
Introduction The benefits of atropine in the treatment of acute organophosphate (OP) poisoning has been well established, while that of oximes is still uncertain. Pralidoxime is the most often used oxime worldwide.
Himal Kharel, N. Pokhrel, R. Ghimire, Zeni Kharel   +3 more
semanticscholar   +1 more source

Therapy of Organophosphate Poisoning via Intranasal Administration of 2-PAM-Loaded Chitosomes

Pharmaceutics, 2022
Chitosan-decorated liposomes were proposed for the first time for the intranasal delivery of acetylcholinesterase (AChE) reactivator pralidoxime chloride (2-PAM) to the brain as a therapy for organophosphorus compounds (OPs) poisoning.
Elmira A. Vasilieva, Darya A. Kuznetsova, Farida G. Valeeva, Denis M. Kuznetsov, Andrey V. Zakharov, Syumbelya K. Amerhanova, Alexandra D. Voloshina, Irina V. Zueva, Konstantin A. Petrov, Lucia Ya. Zakharova   +9 more
doaj   +1 more source