Results 31 to 40 of about 1,662,226 (149)

Evaluation of Potency of Known Oximes (Pralidoxime, Trimedoxime, HI-6, Methoxime, Obidoxime) to in vitro Reactivate Acetylcholinesterase Inhibited by Pesticides (Chlorpyrifos and Methylchlorpyrifos and Nerve Agent (Russian VX)

Acta Medica, 2007
Nerve agents and pesticides belong to the group of organophosphates. They are able to inhibit irreversibly the enzyme acetylcholinesterase (AChE). Acetylcholinesterase reactivators were designed for the treatment of nerve agent intoxications.
Kamil Musílek, Kamil Kuča, Daniel Jun
doaj   +1 more source

Novel Group of AChE Reactivators—Synthesis, In Vitro Reactivation and Molecular Docking Study

Molecules, 2018
The acetylcholinesterase (AChE) reactivators (e.g., obidoxime, asoxime) became an essential part of organophosphorus (OP) poisoning treatment, together with atropine and diazepam.
David Malinak, Eugenie Nepovimova, Daniel Jun, Kamil Musilek, Kamil Kuca   +4 more
doaj   +1 more source

Evaluation of Pralidoxime Use in an Iranian Teaching Referral Hospital [PDF]

, 2018
Background: Organophosphorus (OP) poisonings, a common source of pesticide poisoning, are an important cause of morbidity and mortality in the developing countries.
Siroos Javani, Maryam Zaare Nahandi, Ali Banagozar Mohammadi, Afshin Gharekhani, Negin Raad   +4 more
core   +1 more source

Pralidoxime in organophosphorus poisoning

, 2010
INTRODUCTION: Pralidoxime are enzyme reactivator that are known to reactivate the phosphorylated acetylcholinesterase by binding to the organophosphorus molecule.
PN Prasad, N R Simkhada, KK Kafle
core   +1 more source

Pharmacological applications of azomethine derivatives in the therapy of different diseases [PDF]

Pharmacia
Compounds with an azomethine structure belong to different chemical classes—they are hydrazones, phenylhydrazones, semicarbazones, thiosemicarbazones, and oximes.
Ivanka Pencheva, Lily Peikova, Dobrina Tsvetkova   +2 more
doaj   +3 more sources

Acute Organophosphate Poisoning Induced Extrapyramidal Syndrome: A Case Report [PDF]

Asia Pacific Journal of Medical Toxicology, 2019
Background: Organophosphorus compound ingestion is one of the most common modes of deliberate self-harm in developing countries like India. Neurological complications are known in acute, intermediate and delayed phases following organophosphate poisoning.
B Saroj Prusty, Kiran Kumar Ramineni, Majed Momin, Krishna mohan Reddy, Safina Perveen   +4 more
doaj   +1 more source

Surgical Treatment for Hemorrhagic Infarction of Small Intestine Caused by Organophosphate Poisoning

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Acute organophosphorus pesticide poisoning (AOPP) may cause intestinal infarction via intra‐abdominal hypertension (IAH) and non‐occlusive mesenteric ischemia (NOMI). Although this complication carries high mortality, early laparotomy, resection of necrotic bowel, and comprehensive therapy can improve survival, as supported by our successfully
Yi‐Yun Sun, Ren‐Jie Song, Wen‐Rui Wang, Xiao‐Fei Huang, Yuan‐Lan Lu, An‐Yong Yu   +5 more
wiley   +1 more source

Miotoxicidade por organofosforados Organophosphate myotoxicity

Revista de Saúde Pública, 1996
Os organofosforados são um grupo de compostos químicos amplamente utilizados em agropecuária como inseticidas, ocasionando intoxicações acidentais em animais e humanos, e mesmo sendo utilizados em tentativas de suicídio.
Maria J. Cavaliere, Edenilson E. Calore, Nilda M. Perez, Flávio Rodrigues Puga   +3 more
doaj   +1 more source

The importance of longitudinal evaluation using DAT‐SPECT in organophosphate‐induced toxic parkinsonism

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao, Yoichiro Kogoh, Hideki Funahashi, Yusei Yanoma, Minako Azuma, Yasushi Ishida, Yoji Hirano   +6 more
wiley   +1 more source

Pralidoxime Continuous Infusion in the Treatment of Organophosphate Poisoning

, 1997
Objective To report a case of organophosphate poisoning treated with a continuous infusion of pralidoxime chloride. Case Summary A 27-year-old white man presented with extreme agitation, muscle weakness and fasciculations, and respiratory failure after ...
Michael I Anstead, Gretchen M Tush
core   +1 more source