Results 31 to 40 of about 28,463 (245)

Anti-Angiogenic Effects and Mechanism of Prazosin [PDF]

open access: yes, 2012
BACKGROUND. Alpha1-adrenoceptors antagonists doxazosin, terazosin, prazosin are commonly prescribed for benign prostate hyperplasia and hypertension. Doxazosin and terazosin exhibit anti-angiogenic effects and apoptotic activities against multiple cell ...
LIAO, CHUN-HOU;GUH, JIH-HWA;CHUEH, SHIH-CHIEH;YU, HONG-JENG   +1 more
core   +1 more source

Effects of Prazosin on Provoked Alcohol Craving and Autonomic and Neuroendocrine Response to Stress in Alcohol Use Disorder

open access: yesAlcoholism: Clinical and Experimental Research, 2020
Background: Chronic alcohol results in changes to stress biology and autonomic arousal contributing to acute alcohol withdrawal symptoms, neuroendocrine tolerance of the hypothalamic-pituitary-adrenal (HPA) axis responses, high stress-induced craving ...
Verica Milivojevic   +4 more
semanticscholar   +1 more source

Case series: Continued remission of PTSD symptoms after discontinuation of prazosin

open access: yesFrontiers in Psychiatry, 2023
Post-traumatic stress disorder is a debilitating chronic illness that affects 6 out of 100 adults after a severe trauma. The alpha-adrenergic antagonist prazosin, which is prescribed off-label for flashbacks and nightmares due to trauma, is often ...
Christie Richardson   +3 more
doaj   +1 more source

Prazosin inhibits the proliferation and survival of acute myeloid leukaemia cells through down-regulating TNS1.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
BACKGROUND Prazosin, a non-selective α1-adrenoceptor and a selective α2B-adrenoceptor antagonist, is reported to possess anti-cancer activity in some types of cancer.
Xiaogang Sun, Shuping Yang, Wei Song
semanticscholar   +1 more source

Retrospective Study of Children with Scorpion Envenomation in a Tertiary Care Center of North India [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2020
Background:  Scorpion envenomation is a common public health problem worldwide and children are at greater risk of developing severe cardiac, respiratory and neurological complications.
Rajesh Yadav   +4 more
doaj   +1 more source

Brain activation and subjective anxiety during an anticipatory anxiety task is related to clinical outcome during prazosin treatment for alcohol use disorder

open access: yesNeuroImage: Clinical, 2020
Background: Higher levels of anxiety, negative affect, and impaired emotion regulation are associated with alcohol use disorder (AUD) and contribute to relapse and worse treatment outcomes.
Claire E. Wilcox   +8 more
doaj   +1 more source

Sleep Disturbances Among Yazidi Survivors of the ISIS Genocide: Epidemiology, Neuropsychology, and Culturally Sensitive Interventions. [PDF]

open access: yesBrain Behav
The figure presents an integrative model of sleep disturbances among Yazidi survivors of the 2014 genocide perpetrated by the Islamic State (ISIS). Genocide‐related trauma, including mass violence, sexual violence, displacement, and historical trauma, is associated with sustained neurobiological dysregulation, including hypothalamic–pituitary–adrenal ...
Kizilhan JI, Ag Z, Ahmed QA, Avidan AY.
europepmc   +2 more sources

Super-Resolution Ultrasound Imaging Can Quantify Alterations in Microbubble Velocities in the Renal Vasculature of Rats

open access: yesDiagnostics, 2022
Super-resolution ultrasound imaging, based on the localization and tracking of single intravascular microbubbles, makes it possible to map vessels below 100 µm. Microbubble velocities can be estimated as a surrogate for blood velocity, but their clinical
Sofie Bech Andersen   +6 more
doaj   +1 more source

Some new prazosin analogues. [PDF]

open access: yes, 1989
The synthesis and the pharmacological properties of some new prazosin analogues are ...
Valenti P   +6 more
core   +1 more source

Brief review on analysis of Prazosin Hydrochloride [PDF]

open access: yes, 2016
Prazosin is one of the alphaone adrenoreceptor blocker used in hypertension, benign prostatic hyperplasia, prostate cancer etc. The alpha blockers are relatively inexpensive and exert their effects quickly and Prazosin is the most commonly used alpha ...
Shrivastava, Alankar
core   +2 more sources

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