Results 41 to 50 of about 28,463 (245)

An update on epidemiology and management practices of Scorpion envenomation in India

Journal of Family Medicine and Primary Care, 2022
Introduction: Scorpion envenomation is a life-threatening condition, particularly for children. Therefore, it is essential for primary care health providers to suspect, identify, and manage this condition early to prevent death and minimize morbidity ...
Rakesh Kumar
doaj   +1 more source

Effectiveness of Sensitisation Programme on Prazosin Therapy for Scorpion Envenomation at Primary and Secondary Healthcare Level [PDF]

Indian Journal of Neonatal Medicine and Research, 2022
Introduction: Scorpion envenomation is a life-threatening paediatric emergency. Prazosin-an alpha-1 blocker is the gold standard therapy for scorpion envenomation. Many children with scorpion envenomation were under-treated at Primary Healthcare (PHC)
B RAMESHBABU, P PUNITHA, E MANOCHITRA, K SASIKALA, J BALAJI   +4 more
doaj   +1 more source

Synthesis of poly(hydroxypropylglutamine-prazosin carbamate) and release studies [PDF]

, 1991
Prazosin, an antihypertensive drug with postsynaptic α1-aradrenergic blocking activity, has been coupled to poly-N 5-(3-hydroxypropyl-L-glutamine) (PHPG) via a carbamate linkage.
Bennet, D.B., Li, Xiaoling, Adams, N.W., Adams, Nathan W., Bennet, David B., Kim, Sung Wan, Li, X., Feijen, Jan   +7 more
core   +1 more source

Avocado Oil Prevents Kidney Injury and Normalizes Renal Vasodilation after Adrenergic Stimulation in Hypertensive Rats: Probable Role of Improvement in Mitochondrial Dysfunction and Oxidative Stress

Life, 2021
Hypertension impairs the function of the kidney and its vasculature. Adrenergic activation is involved in these processes by promoting oxidative stress and mitochondrial dysfunction.
Cristian Adrián Márquez-Ramírez, Berenice Eridani Olmos-Orizaba, Claudia Isabel García-Berumen, Elizabeth Calderón-Cortés, Rocío Montoya-Pérez, Alfredo Saavedra-Molina, Alain Raimundo Rodríguez-Orozco, Christian Cortés-Rojo   +7 more
doaj   +1 more source

Comparative efficacy of imagery rehearsal therapy and prazosin in the treatment of trauma-related nightmares in adults: A meta-analysis of randomized controlled trials.

Sleep Medicine Reviews, 2019
Pharmacological treatment with prazosin and psychological treatment with imagery rehearsal therapy (IRT) are the two main treatments of posttraumatic nightmares.
Dilan Yücel, A. V. van Emmerik, Camille Souama, J. Lancee   +3 more
semanticscholar   +1 more source

Tissue compatibility of poly(hydroxypropylglutamate)-prazosin conjugates [PDF]

, 1992
Biocompatibility of an injectable biodegradable drug delivery system for prazosin was investigated in Sprague-Dawley rats by histological studies after subcutaneous injection ofpoly(hydroxypropyl glutamate)-prazosin (PHPG-prazosin) conjugate particles ...
Li, Xiaoling, Kim, Sung Wan, Yamaguchi, Kazuhiro, Feijen, Jan, Anderson, James M.   +4 more
core   +1 more source

Partial agonist activity of α1-adrenergic receptor antagonists for chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3.

PLoS ONE, 2018
We observed in PRESTO-Tango β-arrestin recruitment assays that the α1-adrenergic receptor (AR) antagonist prazosin activates chemokine (C-X-C motif) receptor (CXCR)4. This prompted us to further examine this unexpected pharmacological behavior.
Xianlong Gao, Hazem Abdelkarim, Lauren J Albee, Brian F Volkman, Vadim Gaponenko, Matthias Majetschak   +5 more
doaj   +1 more source

Pediatric scorpionism in southwest Turkey: the experience of a training and research hospital

Acta Medica Alanya, 2022
Aim: The aim of this study was to evaluate the clinical and laboratory features and prognosis of scorpion stings in children.Methods: This was a retrospective study of children with scorpion stings, who were admitted to the pediatric emergency department
Ayça Esra Akkaya Kuybulu, Duygu Çalışkan   +1 more
doaj   +1 more source

Formulation and evaluation of prazosin hydrochloride loaded solid lipid nanoparticles: PRAZOSIN HYDROCHLORIDE LOADED SOLID LIPID NANOPARTICLES [PDF]

, 2018
Solid Lipid Nanoparticles (SLN) are rapidly developing field of nanotechnology with several potential application in drug delivery and research. Drugs having low aqueous solubility not only give low oral bioavailability but provide high inter-and intra ...
Shelake, Sardar, Patil, Shitalkumar, Patil, Pravin, Bandgar, Sandip Akaram, Dhavale, Pranali   +4 more
core   +1 more source

MH-76, a Novel Non-Quinazoline α₁-Adrenoceptor Antagonist, but Not Prazosin Reduces Inflammation and Improves Insulin Signaling in Adipose Tissue of Fructose-Fed Rats

Pharmaceuticals, 2021
Background: Quinazoline α1-adrenoceptors antagonists have been shown to exert moderately favorable effects on the metabolic profile in hypertensive patients.
Monika Kubacka, Szczepan Mogilski, Monika Zadrożna, Barbara Nowak, Małgorzata Szafarz, Bartosz Pomierny, Henryk Marona, Anna Waszkielewicz, Wojciech Jawień, Jacek Sapa, Marek Bednarski, Joanna Knutelska, Magdalena Kotańska   +12 more
doaj   +1 more source