Results 111 to 120 of about 9,210,402 (249)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Frequency of pre-analytical errors in a tertiary hospital clinical laboratory, north-central Nigeria

, 2018
Background: The generation of accurate and reliable laboratory results is the main objective of any clinical laboratory service. The total testing process is broadly divided into pre-analytical, analytical and post-analytical phases.
Ogundeko, Olugbenga T., Isa, Hezekiah A., Daniel, Freeman D., Ramyil, Seljul M., Jonah, Peter Y.   +4 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The pre-analytical challenges of routine urinalysis

, 2010
An effective diagnostic strategy for urinalysis should be based on standard procedures for collection, transport, sample preparation and analysis. In view of a better reproducibility of the analyses, the pre-analytical requirements become stricter ...
Coppens, A, Speeckaert, Marijn, Delanghe, Joris   +2 more
core  

Assessment of the pre-analytical phase of a clinical analyses laboratory

, 2018
Introduction: The pre-analytical phase encompasses the procedures prior to the performance of the laboratory tests, which are the physician's requisition, patient and tests registration, collection and transport of samples.
Flávia Martinello (5835698), Jéssica M. Martins (5835692), Elayne Cristina M. Rateke (5835695)   +2 more
core   +1 more source

Implementing Green Analytical Methodologies Using Solid-Phase Microextraction: A Review

, 2020
Implementing green analytical methodologies has been one of the main objectives of the analytical chemistry community for the past two decades. Sample preparation and extraction procedures are two parts of analytical method development that can be best ...
Amanda R. Dershem, Kayla M. Billiard, Emanuela Gionfriddo   +2 more
core   +1 more source

Effect of blood collection tube variability on biochemistry test reliability: focus on possible contamination and other discrepancies

Türk Biyokimya Dergisi
The aim of this study was to evaluate the effects of five different brands of gel separator biochemistry serum tubes (BD-Vacutainer, Greiner Bio One-Vacuette, Samplix, Pirmax and Ayset) on routine biochemistry test measurement results performed with both
Balci Tevfik, Ayan Durmuş, Zeybek Aydoğan Kader, Küçükkaya Onur, Demirtaş Ayşe, Özdemir Muammer, Bayram Ergül, Bayraktar Bariş   +7 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source