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Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei
Journal of Cell Science, 2000ABSTRACT As the first step in determining whether or not pre-replication complexes are assembled at specific sites along mammalian chromosomes, nuclei from G1-phase hamster cells were incubated briefly in Xenopus egg extract in order to initiate DNA replication.
C J, Li +3 more
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Interaction and Assembly of Murine Pre-replicative Complex Proteins in Yeast and Mouse Cells
Journal of Molecular Biology, 2003Eukaryotic cells coordinate chromosome duplication by the assembly of protein complexes at origins of DNA replication by sequential binding of member proteins of the origin recognition complex (ORC), CDC6, and minichromosome maintenance (MCM) proteins.
Margot, Kneissl +3 more
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New insights in pre-replication complex formation with single-molecule visualization
Science Bulletin, 2015Huijun Xue, Xin Xu, Yu V. Fu
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[Emerging roles for components of pre-replication complexes in chromosomal dynamics].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2011openaire +1 more source
How Mcm10 converts the pre-replication complex into two diverging DNA forks
Nature Structural & Molecular Biologyopenaire +1 more source
SYK inhibition potentiates EGFR-targeted therapy by compromising the pre-replication complex
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