Results 101 to 110 of about 2,341,004 (362)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

On Some Aspects of the Participation of Experts and Specialists in Criminal Proceedings in the Republic of Kazakhstan

open access: yesТеория и практика судебной экспертизы
The article considers particular reasons for the start of a pre-trial investigation, which are associated with the participation of persons having specialized knowledge in the proceedings.By using a number of methods of cognition of the circumstances of ...
K. K. Seitenov, A. Z. Saken
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Historical background to the formation of the forensic doctrine on neutralising investigation counteraction

open access: yesBulletin of Kharkiv National University of Internal Affairs
The article substantiates that in the course of historical development of mankind, counteraction to an investigation naturally accompanies such a form of social activity as criminal activity, and therefore, is a substantive component of criminal activity.
O. M. Tarkan
doaj   +1 more source

Features of Criminal Proceedings (Pre-Trial and Trial Investigation) in the Time of Pandemic Covid-19

open access: yes, 2020
The work is devoted to the main problems and features that have emerged in the field of criminal justice (pre-trial investigation and trial) in a pandemic.
L. Bielik   +4 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Деякі аспекти забезпечення прав учасників кримінального провадження під час ознайомлення з матеріалами досудового розслідування [PDF]

open access: yes, 2015
Паршак, С. А. Деякі аспекти забезпечення прав учасників кримінального провадження під час ознайомлення з матеріалами досудового розслідування / Паршак Сергій Анатолійович // Наше право. - 2015. - № 4. - С. 126-130.Паршак С. А. "Деякі аспекти забезпечення
Parshak, S. A., Паршак, С. А.
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Disclosure of evidence in pre-trial proceedings and investigation [PDF]

open access: yesStrani pravni život, 2020
Disclosure of evidence to the defendant and defense counsel during pre-trial proceedings and investigations is important for the defendant to be able to devise a defense strategy and to suggest the taking of other evidentiary actions during the ...
Živković Natalija M.
doaj  

Функции квесторов архаического Рима в уголовном судопроизводстве [PDF]

open access: yes, 2009
Вопрос о функциях римских квесторов в сфере уголовного судопроизводства нуждается в специальном исследовании по нескольким причинам: во-первых, для изучения ранних форм уголовного процесса в Риме, во-вторых, для исследования проблемы происхождения ...
Dement'eva, Vera Viktorovna   +1 more
core  

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