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The complex physicochemical structures and chemical reactions in living organism have some common features: (1) The life processes take place in the cytosol in the cells, which, from a physicochemical point of view is an emulsion of biomolecules in a dilute aqueous suspension.
arxiv +1 more source
DNA Renaturation at the Water-Phenol Interface [PDF]
We study DNA adsorption and renaturation in a water-phenol two-phase system, with or without shaking. In very dilute solutions, single-stranded DNA is adsorbed at the interface in a salt-dependent manner.
121+161 more
core +3 more sources
The Future of Prebiotic Chemistry
Two recent papers reporting advances in our understanding of how a protometabolism may have developed in a prebiotic world add new meaning to the theme “First Reactions” and highlight the challenges facing synthetic organic chemists attempting to retrodict the origins of life.
Alexander J. Wagner, Donna G. Blackmond
openaire +3 more sources
Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen+9 more
wiley +1 more source
: Cigarette smoke in large centers is one of the most important causes of chronic inflammatory diseases in public health and is associated with a decrease in bone mass, consolidation process, and bone remodeling.
Marcelo Fernandes Tribst+9 more
doaj +1 more source
On the origin of the standard genetic code as a fusion of prebiotic single-base-pair codes [PDF]
The genesis of the stand genetic code is considered as a result of a fusion of two AU- and GC-codes distributed in two dominant and two recessive domains. The fusion of these codes is described with simple empirical rules. This formal approach explains the number of the proteinogenic amino acids and the codon assignment in the resulting standard ...
arxiv
Remnants of an ancient metabolism without phosphate [PDF]
Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E.+3 more
core +1 more source
Introduction. Prebiotic factor, such as inulin, is able to stimulate the growth of bifidobacteria selectively at the expense of more putrefactive bacteria. Chemical structure - Inulin has been defined as carbohydrate material consisting of ? (2-1) fructosyl-fructose links.
Zdenka Sokic+2 more
openaire +3 more sources
This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong+5 more
wiley +1 more source
Inulin‐type fructans and short‐chain fructooligosaccharides are becoming and increasingly common ingredient used in the food industry as fat and sugar replacers and texture modifiers. Yet careful consideration must be given to the type and quantity of fructans used in replacement of fat and sugar in order product integrity while maintaining product ...
Peter Philip James Jackson+2 more
wiley +1 more source