Results 151 to 160 of about 77,082 (360)

Chemical Evolution of Early Macromolecules: From Prebiotic Oligopeptides to Self‐Organizing Biosystems via Amyloid Formation

Chemistry – A European Journal, Accepted Article.
Short amyloidogenic oligopeptides (APRs) are proposed as early macromolecules capable of forming solvent‐separated nanosystems under prebiotic conditions. This study provides experimental evidence that APRs, such as the aggregation‐prone oligopeptide A (APR‐A), can undergo mutational transitions to form distinct variants, and convert to APR‐B, either ...
Fruzsina Bencs, Nóra Taricska, Zsolt Dürvanger, Dániel Horváth, Zsolt Fazekas, Vince Grolmusz, Viktor Farkas, András Perczel   +7 more
wiley   +1 more source

The Effects of Dehydration Temperature and Monomer Chirality on Primitive Polyester Synthesis and Microdroplet Assembly

Macromolecular Chemistry and Physics, Volume 223, Issue 23, December 2022., 2022
Polyesters synthesized prebiotically through dehydration synthesis of α‐hydroxy acids can assembly into membraneless microdroplets proposed to be primitive compartment models. Here, in order to more widely probe the conditions amenable to such primitive polyester microdroplet formation, the effects of synthesis temperature and monomer chirality on ...
Rehana Afrin, Chen Chen, Davide Sarpa, Mahendran Sithamparam, Ruiqin Yi, Chaitanya Giri, Irena Mamajanov, H. James Cleaves II, Kuhan Chandru, Tony Z. Jia   +9 more
wiley   +1 more source

Molecular Imprinting: The missing piece in the puzzle of abiogenesis? [PDF]

arXiv, 2018
In a neglected 2005 paper, Nobel Laureate Paul Lauterbur proposed that molecular imprinting in amorphous materials -- a phenomenon with an extensive experimental literature -- played a key role in abiogenesis. The present paper builds on Lauterbur's idea to propose imprint-mediated templating (IMT), a mechanism for prebiotic peptide replication that ...
arxiv  

Prebiotics and synbiotics: concepts and nutritional properties [PDF]

, 1998
Marcel Roberfroid
openalex   +1 more source

Non-digestible oligosaccharides used as prebiotic agents: mode of production and beneficial effects on animal and human health [PDF]

, 1999
Damien Grizard, Chantal Barthomeuf
openalex   +1 more source

Homochirality through Photon-Induced Melting of RNA/DNA: the Thermodynamic Dissipation Theory of the Origin of Life [PDF]

, 2010
The homochirality of the molecules of life has been a vexing problem with no generally accepted solution to date. Since a racemic mixture of chiral nucleotides frustrates the extension and replication of RNA and DNA, understanding the origin of ...
Karo Michaelian
core   +2 more sources

Origin of Life

, 2012
The evolution of life has been a big enigma despite rapid advancements in the fields of biochemistry, astrobiology, and astrophysics in recent years.
A. Gibbons, Ashwini Kumar Lal, C. Bohler, C. Chyba, C. Huber, C.E. Manning, C.J. Salter, D. Penny, D. Warmflash, D.S. Heckman, D.S. Mckay, E.G. Roussel, F. Hoyle, F. Hoyle, F. Hoyle, G.F. Joyce, H.C. Arp, H.C. Urey, J. Li, J. Maddox, J. Postgate, J.B.S. Haldane, J.K. Fredrickson, J.V. Narlikar, J.W. Schopf, K. Kvenvolden, L.-H. Lin, L.E. Orgel, L.J. Richardson, M.T. Mondigan, N.C. Wickramsinghe, P. David, P. Ehrenfreund, P. Senapathy, R. Shapiro, R.D. Lorenz, S Arrhenius, S.J. Mojzsis, S.L. Miller, S.L. Miller, Stofan, T. Brock, T.D. Brack, W. Gilbert, W. Martin, Y.-J. Kuan, Y.-J. Ma   +46 more
core   +1 more source

Beneficial and anti-inflammatory effects of formulated prebiotics, probiotics, and synbiotics in normal and acute colitis mice

Journal of Functional Foods, 2022
In inflammatory bowel disease (IBD), an altered gut microbiota is observed and is a proposed causal factor for compromised intestinal integrity and disease progression.
Wing-Yan Wong, Brandon Dow Chan, Tsz-Wing Leung, ManXin Chen, William Chi-Shing Tai   +4 more
doaj  

Thermodynamics of prebiotic synthesis [PDF]

arXiv
In this paper, I outline the correspondence of vector partitions with the combinatorics of dynamical systems whose states are partitions of multisets. I use the notion of a limiting shape of vector partitions to determine properties of the equilibrium distribution for these systems.
arxiv  

Advances and Challenges in the Development of Immobilized Enzymes for Batch and Flow Biocatalyzed Processes

ChemSusChem, EarlyView.
Recent advancements in the preparation of immobilized enzymes have improved both batch and continuous flow biocatalytic processes, essential for cost‐effective, sustainable production in the fine chemicals and pharmaceutical industries. This review examines advancements in carrier‐free methods, entrapment strategies, and support‐based approaches ...
Stefania Patti, Ilaria Magrini Alunno, Sara Pedroni, Sergio Riva, Erica Elisa Ferrandi, Daniela Monti   +5 more
wiley   +1 more source