Results 31 to 40 of about 116,118 (329)
The origin of life is in a sense a genetic problem, for, as H. J. Muller pointed out many years ago, the essential attribute that identifies living matter is its capacity to replicate itself and its variants (1). Because this uniquely biological property
Horowitz, N. H., Hubbard, Jerry S.
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Prebiotic synthesis of cysteine peptides that catalyze peptide ligation in neutral water
Cysteine as peptide precursor and catalyst Among amino acids, cysteine is highly reactive as a nucleophile, metal ligand, and participant in redox and radical reactions. These properties make cysteine attractive as a component of prebiotic chemistry, but
Callum S. Foden+5 more
semanticscholar +1 more source
Prebiotic Potential of Cereal Components
One type of functional food that has been receiving much attention is food rich in prebiotics. The old but still valid definition of prebiotics defines them as non-digestible food components that selectively stimulate the growth and/or activity of the ...
Reihaneh Abdi, I. Joye
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The origins and physical roots of life’s dual – metabolic and genetic – nature [PDF]
This review paper aims at a better understanding of the origin and physical foundation of life’s dual – metabolic and genetic – nature. First, I give a concise ‘top-down’ survey of the origin of life, i.e., backwards in time from extant DNA/RNA/protein ...
De Tiège, Alexis
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Prebiotic digestion and fermentation [PDF]
Prebiotics, as currently conceived of, are all carbohydrates of relatively short chain length. To be effective they must reach the cecum. Present evidence concerning the 2 most studied prebiotics, fructooligosaccharides and inulin, is consistent with their resisting digestion by gastric acid and pancreatic enzymes in vivo.
John H. Cummings+2 more
openalex +4 more sources
Modern views of ancient metabolic networks [PDF]
Metabolism is a molecular, cellular, ecological and planetary phenomenon, whose fundamental principles are likely at the heart of what makes living matter different from inanimate one. Systems biology approaches developed for the quantitative analysis of
Goldford, Joshua E., Segrè, Daniel
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Remnants of an ancient metabolism without phosphate [PDF]
Phosphate is essential for all living systems, serving as a building block of genetic and metabolic machinery. However, it is unclear how phosphate could have assumed these central roles on primordial Earth, given its poor geochemical accessibility.
Goldford, Joshua E.+3 more
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In vitro screening of probiotic lactic acid bacteria and prebiotic glucooligosaccharides to select effective synbiotics [PDF]
Probiotics and prebiotics have been demonstrated to positively modulate the intestinal microflora and could promote host health. Although some studies have been performed on combinations of probiotics and prebiotics, constituting synbiotics, results on ...
Courtin, Céline+6 more
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Prebiotic effects: metabolic and health benefits
The different compartments of the gastrointestinal tract are inhabited by populations of micro-organisms. By far the most important predominant populations are in the colon where a true symbiosis with the host exists that is a key for well-being and ...
M. Roberfroid+20 more
semanticscholar +1 more source
Nitrogen Oxide Concentrations in Natural Waters on Early Earth
A key challenge in origins-of-life studies is estimating the abundances of species relevant to the chemical pathways proposed to have contributed to the emergence of life on early Earth.
Babbin, Andrew R.+4 more
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