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Rethinking “Prebiotic Chemistry” [PDF]
In origins‐of‐life research, the term “prebiotic chemistry” is commonly used to describe processes thought to be related to or required for the emergence of life.
Michael L. Wong +2 more
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Prebiotic Chemistry Experiments Using Microfluidic Devices [PDF]
Microfluidic devices are small tools mostly consisting of one or more channels, with dimensions between one and hundreds of microns, where small volumes of fluids are manipulated. They have extensive use in the biomedical and chemical fields; however, in
Karen Melissa Lerin-Morales +3 more
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Prebiotic Chemistry: The Role of Trimetaphosphate in Prebiotic Chemical Evolution [PDF]
Life’s origins have always been a scientific puzzle. Understanding the production of biomolecules is crucial for understanding the evolution of life on Earth.
Dingwei Gan +6 more
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The protometabolic nature of prebiotic chemistry.
This tutorial review revises the main synthetic pathways of prebiotic chemistry, suggesting how they could be wired through common intermediates and catalytic cycles, as well as the boundary conditions under which they would become protometabolic.
Nogal N +4 more
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A Physicochemical Consideration of Prebiotic Microenvironments for Self-Assembly and Prebiotic Chemistry [PDF]
The origin of life on Earth required myriads of chemical and physical processes. These include the formation of the planet and its geological structures, the formation of the first primitive chemicals, reaction, and assembly of these primitive chemicals ...
Arpita Saha +4 more
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Prebiotic chemistry and human intervention [PDF]
Experimentalists in the field of prebiotic chemistry strive to re-enact what may have happened when life arose from inanimate material. How often human intervention was needed to obtain a specific result in their studies is worth reporting.
Clemens Richert
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Prebiotic Chemistry: Geochemical Context and Reaction Screening [PDF]
The origin of life on Earth is widely believed to have required the reactions of organic compounds and their self- and/or environmental organization. What those compounds were remains open to debate, as do the environment in and process or processes by ...
Henderson James Cleaves
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Heat flows solubilize apatite to boost phosphate availability for prebiotic chemistry [PDF]
Phosphorus is an essential building block of life, likely since its beginning. Despite this importance for prebiotic chemistry, phosphorus was scarce in Earth’s rock record and mainly bound in poorly soluble minerals, with the calcium-phosphate mineral ...
Thomas Matreux +12 more
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The Future of Prebiotic Chemistry [PDF]
Two recent papers reporting advances in our understanding of how a protometabolism may have developed in a prebiotic world add new meaning to the theme “First Reactions” and highlight the challenges facing synthetic organic chemists attempting to retrodict the origins of life.
Alexander J. Wagner, Donna G. Blackmond
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Phosphorus in prebiotic chemistry [PDF]
The prebiotic synthesis of phosphorus-containing compounds—such as nucleotides and polynucleotides—would require both a geologically plausible source of the element and pathways for its incorporation into chemical systems on the primitive Earth. The mineral apatite, which is the only significant source of phosphate on Earth, has long been thought to be
Alan W. Schwartz
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