Results 101 to 110 of about 57,100 (293)

GH172 Difructose Dianhydride I Synthase: A Two‐Stepped Journey via Glycosylation and Cyclization Using QM/MM Metadynamics

open access: yesChemistry – A European Journal, EarlyView.
Unlocking the chemistry of caramel by simulations and experimental validation. αFFase1${\alpha }\rm{FFase1}$ converts inulobiose into difructose dianhydride I, one component of caramel, through two steps: a rate‐limiting glycosylation (with a rare sugar ring flip) followed by a cyclization step, guided by residues E85, K147, and N226.
Santiago Alonso‐Gil   +7 more
wiley   +1 more source

Reversible Cystine Disulfide Scaffolding Enables Carbonyl Sulfide‐Mediated Intramolecular Peptide Bond Formation via Cyclocystine: Implications for Prebiotic Chemistry

open access: yesChemistry – A European Journal, EarlyView.
Cystine is unique among amino acids, in that the disulfide bond can allow intramolecular peptide bond formation. This cyclization offers potential advantages for intramolecular coupling selectivity in prebiotic peptide formation. ABSTRACT Treatment of cystine (the disulfide‐linked dimer of cysteine) with carbonyl sulfide (COS) results in the formation ...
Avinash Vicholous Dass   +5 more
wiley   +1 more source

Uncatalyzed Guanosine Phosphorylation under Potentially Prebiotic Conditions

open access: yesChemistry – A European Journal, EarlyView.
Pyrophosphate acts as phosphorylating agent of guanosine under simple wet‐dry cycles without condensing agent and inorganic catalysts to afford cyclic guanosine monophosphate derivatives useful for oligomerization in prebiotic processes. ABSTRACT The phosphorylation of nucleosides and their subsequent polymerization are key issues in the study of the ...
Martina Proietti   +5 more
wiley   +1 more source

The effects of synbiotics surpass prebiotics in improving inflammatory biomarkers in children and adults: A systematic review, meta-analysis, and meta-evidence of data from 5207 participants in 90 randomized controlled trials

open access: yesPharmacological Research
Several trials have revealed the beneficial effects of synbiotics on inflammatory biomarkers. Nevertheless, the findings drawn from extant trials remain contentious.
Yining Zhang   +4 more
doaj   +1 more source

Glycosaminoglycans of human milk during the first month of lactation: further potential prebiotics for the breastfed infant

open access: yes, 2011
Glycosaminoglycans of human milk during the first month of lactation: further potential prebiotics for the breastfed ...
VOLPI, Nicola   +7 more
core  

Chemical engineering as an essential element of industrial biotechnology in Mexico: New aims in research and university education

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
Abstract On the centennial of higher education in Chemical Engineering in Mexico, it is pertinent to revisit the key stages that have contributed to its consolidation as a vital discipline for the nation's scientific and technological advancement. Although the initial mission of chemical engineering education was primarily oriented toward the training ...
Agustín López Munguía   +3 more
wiley   +1 more source

Modifiable Transdiagnostic Risk and Protective Factors as Potential CBT Augmentation Targets for Eating Disorders: An Updated Umbrella Review

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective A focus on transdiagnostic targets is one of the key strategies for developing effective, efficient, and scalable treatments for mental health conditions. We conducted an umbrella review of recent meta‐analyses (August 2022 to May 2026) to update our understanding of critical transdiagnostic intervention targets that could inform ...
Yuan Zhou   +2 more
wiley   +1 more source

Knowledge and awareness of Palestinian health care professionals towards probiotics, prebiotics and synbiotics: a cross-sectional study from Palestine

open access: yesJournal of Biological Research
Probiotics are live microorganisms believed to confer health benefits when consumed appropriately. Prebiotics are non-digestible food components that promote health by encouraging the growth or activity of beneficial microorganisms.
Abdel Naser Zaid   +10 more
doaj   +1 more source

Prebiotics Improve Blood Pressure Control by Modulating Gut Microbiome Composition and Function: A Systematic Review and Meta-Analysis

open access: yes
<b>Background:</b> Ingestion of dietary fibers (DFs) is a safe and accessible intervention associated with reductions in blood pressure (BP) and cardiovascular mortality.
Wang, Elisabeth M.   +5 more
core   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy