Results 71 to 80 of about 47,692 (297)

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Por que seguir precedentes? [PDF]

open access: yes, 2017
Relata o surgimento do Estado do Direito e seus fundamentos, bem como sua formação a partir da teoria da separação de Poderes idealizada por Montesquieu. Disserta sobre os princípios da segurança jurídica, da liberdade e da igualdade, relacionando-os com
Machado, Priscila Maíra Lucas da Silva
core   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu   +10 more
wiley   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

open access: yesAdvanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis   +8 more
wiley   +1 more source

LITIGIOSIDADE REPETITIVA E PADRONIZAÇÃO DECISÓRIA: O INCIDENTE DE RESOLUÇÃO DE DEMANDAS REPETITIVAS E SUA CONSOLIDAÇÃO PERANTE O SUPERIOR TRIBUNAL DE JUSTIÇA

open access: yesRevista Acadêmica, 2021
Este artigo tem por escopo o estudo sobre o incidente de resolução de demandas repetitivas, novo mecanismo processual inaugurado com o Código de Processo Civil de 2015.
Patrícia Almeida Campos Borges
doaj  

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

open access: yesAdvanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu   +3 more
wiley   +1 more source

Teoria dos precedentes judiciais e sua eficácia para garantia da segurança jurídica / Theory of legal precedent and its effectiveness of legal warranty for safety

open access: yesRevista da Faculdade de Direito da Universidade de Uberlândia, 2014
O presente estudo refere-se à Teoria dos Precedentes Judiciais, demonstrando sua utilização e efeitos no Brasil. Inicia-se a pesquisa pela diferenciação dos sistemas jurídicos Civil Law e Common Law.
Déborah Caron
doaj   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

open access: yesAdvanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena   +3 more
wiley   +1 more source

Análise da jurisprudência do Conselho Nacional de Justiça através de Redes Complexas

open access: yesRevista CNJ, 2019
A partir de dados de jurisprudência do Conselho Nacional de Justiça foram extraídas 9.106 decisões entre 2005 e 2019 e verificados quais precedentes cada decisão judicial citava.
Aline Macohin
doaj   +3 more sources

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