Results 251 to 260 of about 303,204 (352)

Practical considerations for clinical translation of PET imaging of adoptive cell therapies. [PDF]

Npj Imaging
Volpe A, Pham J, Sellmyer MA, Ponomarev V.   +3 more
europepmc   +1 more source

Figure S1-S14, Table S1-S2 & S4-S6 from Osteosarcoma PDX-Derived Cell Line Models for Preclinical Drug Evaluation Demonstrate Metastasis Inhibition by Dinaciclib through a Genome-Targeted Approach [PDF]

Courtney R. Schott, Amanda Koehne, Leanne C. Sayles, Elizabeth P. Young, Cuyler Luck, Katharine Yu, Alex G. Lee, Marcus R. Breese, Stanley G. Leung, Hang Xu, Avanthi Tayi Shah, Heng-Yi Liu, Aviv Spillinger, Inge H. Behroozfard, Kieren D. Marini, Phuong Dinh, María V. Pons Ventura, Emma N. Vanderboon, Florette K. Hazard, Soo‐Jin Cho, Raffi S. Avedian, David G. Mohler, Melissa N. Zimel, Rosanna Wustrack, Christina Curtis, Marina Sirota, E. Alejandro Sweet‐Cordero   +26 more
openalex   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

The zebrafish in toxicology: a bibliometric analysis reveals current trends and future avenues for predictive safety assessment. [PDF]

Front Toxicol
Lima C, Gusso D, Disner GR, Pinto FJ, Falcão MAP, Rosa JGS, Lopes-Ferreira M.   +6 more
europepmc   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

The rapidly growing landscape of RAS inhibitors: from selective allele blockade to broad inhibition strategies. [PDF]

Mol Oncol
Drosten M, Barbacid M.
europepmc   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Special Issue "Advances in Antiviral Agents Against SARS-CoV-2 and Its Variants" 2nd Edition. [PDF]

Viruses
Esposito F.
europepmc   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Strategic Preparedness of Broad-Spectrum Antivirals for Rapid Response Towards Next Pandemics. [PDF]

Small Sci
N SR, Jin GW, Choy JH.
europepmc   +1 more source