Journal of Experimental & Clinical Cancer Research, 2018 Background Bone tissue is one of the main sites for breast metastasis; patients diagnosed with advanced breast cancer mostly develop bone metastasis characterized by severe osteolytic lesions, which heavily influence their life quality.
Valeria Carina +8 more
doaj +1 more source
Neuroinflammation in Preclinical Alzheimer's Disease: A Review of Current Evidence [PDF]
, 2018 The pathology of sporadic Alzheimer’s disease (AD) may be present at mid-life and precede the prodromal and clinical dementia syndromes associated with the disorder by decades.
Raymont, Vanessa +2 more
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Brain amyloid in preclinical Alzheimer\u27s disease is associated with increased driving risk [PDF]
, 2016 INTRODUCTION: Postmortem studies suggest that fibrillar brain amyloid places people at higher risk for hazardous driving in the preclinical stage of Alzheimer's disease (AD). METHODS: We administered driving questionnaires to 104 older drivers (19 AD, 24
Bernier, Justine N +7 more
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Successful object encoding induces increased directed connectivity in presymptomatic early-onset Alzheimer's disease [PDF]
, 2017 Background: Recent studies report increases in neural activity in brain regions critical to episodic memory at preclinical stages of Alzheimer’s disease (AD).
Alonso López, Joan Francesc +6 more
core +2 more sources
Experimental study of the pharmacological activity of new azaheterocycles derivatives: A literature review [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2022 Diseases associated with the pathology of the cardiovascular system are one of the key causes of death all over the world. In particular, arrhythmia may entail the most severe complications, including unexpected death.
Malika Khaiitova +4 more
doaj +1 more source
The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]
, 2012 This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L +5 more
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An open-label, one-arm, dose-escalation study to evaluate safety and tolerability of extremely low frequency magnetic fields in acute ischemic stroke [PDF]
, 2017 Extremely low frequency magnetic fields (ELF-MF) could be an alternative neuroprotective approach for ischemic stroke because preclinical studies have demonstrated their effects on the mechanisms underlying ischemic damage. The purpose of this open-label,
Apollonio, Francesca +7 more
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Decreased risk of breast cancer associated with oral bisphosphonate therapy [PDF]
, 2012 Preclinical studies and adjuvant trials using bisphosphonates have found them to have an antitumor effect. Although major advances have been made in chemoprevention strategies with selective estrogen receptor modulators and aromatase inhibitors, their ...
Brufsky, A, Mathew, A
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Scientific Reports, 2022 Lantana camara L. is widely used in folk medicine for alleviation of inflammatory disorders, but studies that proved this folk use and that revealed the molecular mechanism of action in inflammation mitigation are not enough.
Alaa A. El-Banna +5 more
doaj +1 more source
Antitumor activity of an anti-CD98 antibody. [PDF]
, 2015 CD98 is expressed on several tissue types and specifically upregulated on fast-cycling cells undergoing clonal expansion. Various solid (e.g., nonsmall cell lung carcinoma) as well as hematological malignancies (e.g., acute myeloid leukemia) overexpress ...
Cairns, Belinda +11 more
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