Results 11 to 20 of about 814,690 (301)

Pharmacokinetics of Free Oxytetracycline and Oxytetracycline Loaded Cockle Shell Calcium Carbonate-Based Nanoparticle in BALB/c Mice

open access: yesFrontiers in Veterinary Science, 2020
The development and utilization of nano-antibiotics is currently gaining attention as a possible solution to antibiotic resistance. The aim of this study was therefore to determine the pharmacokinetics of free oxytetracycline (OTC) and oxytetracycline ...
Sherifat Banke Idris   +7 more
doaj   +1 more source

Translational perspectives on perfusion-diffusion mismatch in ischemic stroke [PDF]

open access: yes, 2013
Magnetic resonance imaging has tremendous potential to illuminate ischemic stroke pathophysiology and guide rational treatment decisions. Clinical applications to date have been largely limited to trials.
Campbell, Bruce C. V., Macrae, I. Mhairi
core   +1 more source

Preparation, characterization and in vitro cytotoxicity evaluation of free and liposome-encapsulated tylosin

open access: yesOpenNano, 2022
Liposomes are the most attractive and well-known nanoparticles due to their high biocompatibility and biodegradability features which make them display less toxic effects for employing in vivo.
Mohammad Ehsan Saddiqi   +4 more
doaj   +1 more source

Inhibitory effects of low intensity pulsed ultrasound on osteoclastogenesis induced in vitro by breast cancer cells

open access: yesJournal of Experimental & Clinical Cancer Research, 2018
Background Bone tissue is one of the main sites for breast metastasis; patients diagnosed with advanced breast cancer mostly develop bone metastasis characterized by severe osteolytic lesions, which heavily influence their life quality.
Valeria Carina   +8 more
doaj   +1 more source

Ataxia-Telangiectasia Mutated and the Mre11-Rad50-NBS1 Complex:Promising Targets for Radiosensitization [PDF]

open access: yes, 2012
Radiotherapy plays a central part in cancer treatment, and use of radiosensitizing agents can greatly enhance this modality. Although studies have shown that several chemotherapeutic agents have the potential to increase the radiosensitivity of tumor ...
Fujiwara, Toshiyoshi   +2 more
core   +1 more source

Antitumor activity of an anti-CD98 antibody. [PDF]

open access: yes, 2015
CD98 is expressed on several tissue types and specifically upregulated on fast-cycling cells undergoing clonal expansion. Various solid (e.g., nonsmall cell lung carcinoma) as well as hematological malignancies (e.g., acute myeloid leukemia) overexpress ...
Cairns, Belinda   +11 more
core   +1 more source

Experimental study of the pharmacological activity of new azaheterocycles derivatives: A literature review [PDF]

open access: yesĶazaķstannyṇ Klinikalyķ Medicinasy, 2022
Diseases associated with the pathology of the cardiovascular system are one of the key causes of death all over the world. In particular, arrhythmia may entail the most severe complications, including unexpected death.
Malika Khaiitova   +4 more
doaj   +1 more source

TNFα induces Ca2+ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells [PDF]

open access: yes, 2018
BACKGROUND: Tumor necrosis factor-α has been proven an effective anticancer agent in preclinical studies. However, the translation of TNFα from research to clinic has been blocked by significant systemic toxicity and limited efficacy at maximal tolerated
Ji, Xiaoying   +10 more
core   +4 more sources

Decreased risk of breast cancer associated with oral bisphosphonate therapy [PDF]

open access: yes, 2012
Preclinical studies and adjuvant trials using bisphosphonates have found them to have an antitumor effect. Although major advances have been made in chemoprevention strategies with selective estrogen receptor modulators and aromatase inhibitors, their ...
Brufsky, A, Mathew, A
core   +2 more sources

Metabolic profiling of Lantana camara L. using UPLC-MS/MS and revealing its inflammation-related targets using network pharmacology-based and molecular docking analyses

open access: yesScientific Reports, 2022
Lantana camara L. is widely used in folk medicine for alleviation of inflammatory disorders, but studies that proved this folk use and that revealed the molecular mechanism of action in inflammation mitigation are not enough.
Alaa A. El-Banna   +5 more
doaj   +1 more source

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