Results 101 to 110 of about 38,247 (298)

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

open access: yesAdvanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards   +8 more
wiley   +1 more source

Numerical Simulation of One-Phase Flow to Multi-Stage Hydraulically Fractured Horizontal Well [PDF]

open access: yesУчёные записки Казанского университета: Серия Физико-математические науки, 2016
This paper presents a method of numerical simulation of one-phase flow near multi-stage fractured horizontal well in oil reservoir. Differential models for flows within reservoir and within fractures are formulated separately on the basis of Darcy's law.
M.R. Khamidullin
doaj  

Finite Element Preconditioning on Spectral Element Discretizations for Coupled Elliptic Equations

open access: yesJournal of Applied Mathematics, 2012
The uniform bounds on eigenvalues of B^h2−1A^N2 are shown both analytically and numerically by the P1 finite element preconditioner B^h2−1 for the Legendre spectral element system A^N2u¯=f¯ which is arisen from a coupled elliptic system occurred by an ...
JongKyum Kwon   +3 more
doaj   +1 more source

AI‐Directed 3D Printing of Hierarchical Polyurethane Foams

open access: yesAdvanced Science, EarlyView.
Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil   +15 more
wiley   +1 more source

A Relaxed Splitting Preconditioner for the Incompressible Navier-Stokes Equations

open access: yesJournal of Applied Mathematics, 2012
A relaxed splitting preconditioner based on matrix splitting is introduced in this paper for linear systems of saddle point problem arising from numerical solution of the incompressible Navier-Stokes equations.
Ning-Bo Tan, Ting-Zhu Huang, Ze-Jun Hu
doaj   +1 more source

Wave‐Partition‐Governed Dual‐Site Spallation in Single Crystals

open access: yesAdvanced Science, EarlyView.
Crystalline anisotropy shapes shock‐wave propagation and the resulting damage evolution in single crystals. Large‐scale molecular dynamics and damage modeling uncover a dual‐spallation mechanism driven by anisotropic elasticplastic wave separation, which mitigates damage accumulation.
Youlin Zhu   +6 more
wiley   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

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