Results 51 to 60 of about 409,500 (359)

Integrative Modeling of Prefrontal Cortex

Journal of Cognitive Neuroscience, 2017
AbstractpFC is generally regarded as a region critical for abstract reasoning and high-level cognitive behaviors. As such, it has become the focus of intense research involving a wide variety of subdisciplines of neuroscience and employing a diverse range of methods.
James Deraeve, Zachary Langford, Eliana Vassena, Eliana Vassena, William H. Alexander   +4 more
openaire   +4 more sources

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Schizophrenia and reelin: a model based on prenatal stress to study epigenetics, brain development and behavior

Biological Research
Schizophrenia is a severe psychiatric disorder that results in a significant disability for the patient. The disorder is characterized by impairment of the adaptive orchestration of actions, a cognitive function that is mainly dependent on the prefrontal
Ignacio Negrón-Oyarzo, Ariel Lara-Vásquez, Ismael Palacios-García, Pablo Fuentealba, Francisco Aboitiz   +4 more
doaj   +1 more source

Medial prefrontal and anterior insular connectivity in early schizophrenia and major depressive disorder: a resting functional MRI evaluation of large-scale brain network models

Frontiers in Human Neuroscience, 2016
Anomalies in the medial prefrontal cortex, anterior insulae and large-scale brain networks associated with them have been proposed to underlie the pathophysiology of schizophrenia and major depressive disorder (MDD).
Jacob ePenner, Jacob ePenner, Jacob ePenner, Kristen A. Ford, Kristen A. Ford, Kristen A. Ford, Reggie eTaylor, Reggie eTaylor, Betsy eSchaefer, Jean eThéberge, Jean eThéberge, Jean eThéberge, Richard W. J. Neufeld, Richard W. J. Neufeld, Richard W. J. Neufeld, Elizabeth A. Osuch, Elizabeth A. Osuch, Elizabeth A. Osuch, Elizabeth A. Osuch, Ravi S. Menon, Ravi S. Menon, Ravi S. Menon, Nagalingam eRajakumar, Nagalingam eRajakumar, John M. Allman, Peter C. Williamson, Peter C. Williamson, Peter C. Williamson   +27 more
doaj   +1 more source

Specialization of the rostral prefrontal cortex for distinct analogy processes [PDF]

, 2010
Analogical reasoning is central to learning and abstract thinking. It involves using a more familiar situation (source) to make inferences about a less familiar situation (target).
Benoit, R. G., Burgess, P. W., Gilbert, S. J., Volle, E.   +3 more
core   +3 more sources

A Comprehensive Overview of the Clinical, Electrophysiological, and Neuroimaging Features of BPAN: Insights From a New Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun, Ozgu Kizek, Sibel Aylin Ugur Iseri, Ibrahim Kamaci, Ayse Deniz Elmali, Pinar Iscen, Berfin Gulkaya Guzel, Gul Yalcin Cakmakli, Bulent Elibol, Berril Donmez, Raif Cakmur, Pinar Topaloglu, Turkish NBIA Study Group, Abdullah Acar, Ahmet Acarer, Arzu Karabay, Asuman Ali, Ayla Barlas, Aysegul Gunduz, Banu Ozen Barut, Baris Baslo, Bilge Kocer, Bilgehan Mus, Birsen Karaman, Burcu Gokce Cokal, Cem Ismail Kucukali, Cenk Akbostanci, Ceyhun Sayman, Cagla Turan, Dilek Ince Gunal, Ebru Bilge Dirik, Ebru Erzurumluoglu, Elif Kocasoy Orhan, Enes Demiryurek, Emrah Yucesan, Ercan Kose, Erdem Tuzun, Esen Saka Topcuoglu, Esra Okuyucu, Fatma Betul Ozdilek, Feriha Ozer, Gencer Genc, Gozde Unal, Gulay Kenangil, Gullu Tarhan, Gunes Kiziltan, Halil Onder, Hamit Genc, Hasmet Hanagasi, Hatice Yuksel, Hulya Apaydin, Koray Kirimtay, Mehmet Guney Senol, Melisa Kilic, Meltem Demirkiran, Mert Karaca, Miray Erdem, Muhammet Bilgehan Mus, Murat Gultekin, Nalan Capan, Nazan Karagoz Sakalli, Nazli Basak, Nihan Hande Akcakaya, Ozan Ezer, Ozge Uygun, Ozge Yilmaz Kuspeci, Ozgur Oztop Cakmak, Pervin Iseri, Petek Ballar Kirmizibayrak, Pinar Elkoca, Recep Alp, Remzi Yigiter, Rezzak Yilmaz, Sadika Ozdemir, Selda Keskin, Selen Ilhan Alp, Selen Soylu, Serdar Ceylaner, Serhat Ozkan, Sevda Erer Ozbek, Sevgin Gundogan, Sevil Yasufli, Sezin Alpaydin Baslo, Sibel Ertan, Sultan Cagirici, Seyma Aykac, Vuslat Yilmaz, Yaprak Secil, Yasar Kutukcu, Yeliz Ciftci, Yesim Sucullu Karadag, Yildiz Değirmenci, Zeliha Matur, Nerses Bebek, Murat Emre, Zuhal Yapici   +95 more
wiley   +1 more source

Determining monkey free choice long before the choice is made: the principal role of prefrontal neurons involved in both decision and motor processes [PDF]

, 2016
When choices are made freely, they might emerge from pre-existing neural activity. However, whether neurons in the prefrontal cortex (PF) show this anticipatory effect and, if so, in which part of the process they are involved is still debated. To answer
Genovesio, Aldo, Marcos, Encarni
core   +2 more sources

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Neuronal Distortions of Reward Probability without Choice [PDF]

, 2008
Reward probability crucially determines the value of outcomes. A basic phenomenon, defying explanation by traditional decision theories, is that people often overweigh small and underweigh large probabilities in choices under uncertainty.
Christopoulos, George I., Dolan, Raymond J., O'Doherty, John P., Schultz, Wolfram, Tobler, Phillippe N.   +4 more
core   +4 more sources

Bilinearity, rules, and prefrontal cortex [PDF]

Frontiers in Computational Neuroscience, 2007
Humans can be instructed verbally to perform computationally complex cognitive tasks; their performance then improves relatively slowly over the course of practice. Many skills underlie these abilities; in this paper, we focus on the particular question of a uniform architecture for the instantiation of habitual performance and the storage, recall, and
openaire   +5 more sources