Biological ResearchSchizophrenia is a severe psychiatric disorder that results in a significant disability for the patient. The disorder is characterized by impairment of the adaptive orchestration of actions, a cognitive function that is mainly dependent on the prefrontal
Ignacio Negrón-Oyarzo +4 more
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The Medial Prefrontal Cortex in Neurological Diseases.
Physiological Genomics, 2019 The medial prefrontal cortex (mPFC) is a crutial cortical region which integrates information from numerous cortical and subcortical areas and converges updated information to output structures.
Pan Xu +4 more
semanticscholar +1 more source
Gray-matter volume, midbrain dopamine D2/D3 receptors and drug craving in methamphetamine users. [PDF]
, 2015 Dysfunction of the mesocorticolimbic system has a critical role in clinical features of addiction. Despite evidence suggesting that midbrain dopamine receptors influence amphetamine-induced dopamine release and that dopamine is involved in ...
Dean, AC +5 more
core +4 more sources
Context-dependent computation by recurrent dynamics in prefrontal cortex
Nature, 2013 Prefrontal cortex is thought to have a fundamental role in flexible, context-dependent behaviour, but the exact nature of the computations underlying this role remains largely unknown.
Valerio Mante +3 more
semanticscholar +1 more source
What, If Anything, Is Rodent Prefrontal Cortex?
eNeuro, 2018 Visual Abstract Prefrontal cortex (PFC) means different things to different people. In recent years, there has been a major increase in publications on the PFC, especially using mice. However, inconsistencies in the nomenclature and anatomical boundaries
M. Laubach +3 more
semanticscholar +1 more source
Dissociable contributions of the prefrontal cortex to hippocampus- and caudate nucleus-dependent virtual navigation strategies [PDF]
, 2015 The hippocampus and the caudate nucleus are critical to spatial– and stimulus–response-based navigation strategies, respectively. The hippocampus and caudate nucleus are also known to be anatomically connected to various areas of the prefrontal cortex ...
Bohbot, Véronique D., Dahmani, Louisa
core +1 more source
Increased firing irregularity as an emergent property of neural-state transition in monkey prefrontal cortex. [PDF]
PLoS ONE, 2013 Flexible behaviors are organized by complex neural networks in the prefrontal cortex. Recent studies have suggested that such networks exhibit multiple dynamical states, and can switch rapidly from one state to another.
Kazuhiro Sakamoto +5 more
doaj +1 more source
Frontiers in Human Neuroscience, 2021 Resource scarcity imposes challenging demands on the human cognitive system. Insufficient resources cause the scarcity mindset to affect cognitive performance, while reward enhances cognitive function.
Xiaowei Jiang +7 more
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After-effects of 10 Hz tACS over the prefrontal cortex on phonological word decisions
, 2019 Introduction Previous work in the language domain has shown that 10 Hz rTMS of the left or right posterior inferior frontal gyrus (pIFG) in the prefrontal cortex impaired phonological decision-making, arguing for a causal contribution of the bilateral ...
Hartwigsen, G. +6 more
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Determining a Role for Ventromedial Prefrontal Cortex in Encoding Action-Based Value Signals During Reward-Related Decision Making [PDF]
, 2009 Considerable evidence has emerged to implicate ventromedial prefrontal cortex in encoding expectations of future reward during value-based decision making.
Alan N. Hampton +53 more
core +3 more sources