Results 131 to 140 of about 37,679 (252)

Effects of Agomelatine on Sleep Across Populations: A Systematic Review and Meta‐Analysis

Journal of Sleep Research, EarlyView.
ABSTRACT Agomelatine, a melatoninergic antidepressant, is often prescribed to improve sleep disturbance, though meta‐analytic evidence is currently lacking. This systematic review and meta‐analysis assessed its efficacy and tolerability in sleep outcomes compared to placebo.
Anastasios Stefanou, Ioannis Anastasiou, Panagiota Fallon, Eleni Glarou, Nikolaos Christodoulou, Andreas S. Lappas, Vasilios‐Panteleimon Bozikas, Myrto T. Samara   +7 more
wiley   +1 more source

Characterization and Evaluation of the Cytotoxicity of Pregabalin Gels for Oral Application

Pharmaceuticals
The efficacy of pregabalin in pain treatment has led to the search for new formulations for its use through different routes of administration. This study aimed to prepare, characterize, and evaluate the cytotoxicity of pregabalin (PG) gels for topical ...
Gabriela Monteiro Barbosa Xavier, Lindalva Maria de Meneses Costa Ferreira, Marcele Fonseca Passos, Ana Paula Drummond Rodrigues, Felipe Tuji de Castro Franco, Cecy Martins Silva, José Otávio Carréra Silva Júnior, Roseane Maria Ribeiro-Costa, Jesuína Lamartine Nogueira Araújo   +8 more
doaj   +1 more source

Pregabalin dependence: Experiences from liaison psychiatric settings in Kashmir, North India: A case series

Industrial Psychiatry Journal
Pregabalin, a gamma-aminobutyric acid (GABA) analog, is a new-generation antiepileptic that is approved for the treatment of neuropathic pain, fibromyalgia, partial seizures, and generalized anxiety disorder. There is a rising concern regarding its abuse
Aaliya Khanam, Rajnish Raj, Zaid A. Wani, Yasir H. Rather, Iqra Arshad   +4 more
doaj   +1 more source

Possible involvement of keratinocyte‐derived microvesicle particles in human photosensitivity disorders

Photochemistry and Photobiology, EarlyView.
In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M. T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Aadil Umerani, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers   +13 more
wiley   +1 more source

تاثير تك دوز پر هگابالين قبل از عمل بر ميزان درد پس از اعمال كوچك جراحي [PDF]

, 2012
زمينه و هدف: درمان درد حاد بعد از اعمال كوچك جراحي از اهميت ويژهي برخوردار است. پرهگابالين دركنترل دردهاي مزمن نورپاتيك موثر بوده، ولي مطالعات اندكي در مورد تاثير آن در كنترل درد حاد بعد از عمل وجود دارد.
ایمانی, فرناد, حیدریان, مجید, ملاسلطانی, محمد, نظافتی, محمود, نیکنام, کیوان   +4 more
core  

Outcomes of 87 small‐breed dogs surgically treated for Chiari‐like malformation and syringomyelia

Veterinary Surgery, EarlyView.
Abstract Objective To report the outcomes of titanium mesh (TM) cranioplasty without polymethylmethacrylate (PMMA), incorporating a deliberate gap between the foramen magnum decompression (FMD) surface and the TM, in small‐breed dogs with Chiari‐like malformation and syringomyelia (CM/SM). Study design Retrospective clinical study.
Sung Su Park, Ji Young Park, Ho Jae Han
wiley   +1 more source

Linking changes in pain severity to changes in other outcomes in patients with posttraumatic peripheral neuropathic pain treated with pregabalin [POSTER] [PDF]

No abstract ...
Bach, F.W., Bushmakin, A.G., Cappelleri, J.C., Morlion, B.J., Nimour, M., Serpell, M., van Seventer, R., Zlateva, G.   +7 more
core  

اثرات پره گابالین خوراکی در کنترل درد شکستگی اندام تحتانی [PDF]

, 2013
زمينه و هدف: كنترل مناسب درد پس از جراحي از نظر جلوگيري از عوارض منفي همانند تاكيكاردي، افزايش فشارخون، ايسكمي ميوكارد، كاهش تهويه ريوي و بهبود ضعيف زخم ها، اهميت ويژهاي دارد.
اخوان اکبری, قدرت, انتظاری اصل, مسعود, عیسی زاده فر, خاطره, میرزارحیمی, تیبا   +3 more
core  

Pain Management in Aneurysmatic Subarachnoid Haemorrhage: A Survey of Nordic Physicians

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Headache caused by aneurysmatic subarachnoid hemorrhage (aSAH) is often severe and may persist long after the ictus. Pharmacological pain management can be challenging due to poor efficacy or adverse effects. Multimodal pharmacotherapy is often required. Lack of guidelines and good quality clinical studies on pain management has led
Hanna Sariola, Maija‐Liisa Kalliomäki, Heikki Kiiski, Essi Raatikainen, Juhana Frösen, Matti Reinikainen, Hanna Savioja, Kirsten Møller, Terhi Lohela, Riikka Takala, Martin Sigurdsson, Luis Romundstad, Stig Dyrskog, Karsten Bülow, Johanna Hästbacka   +14 more
wiley   +1 more source

Bilateral laryngeal paralysis (aplegia) occurring late during the recovery of a horse after orthopaedic surgery

Equine Veterinary Education, Volume 38, Issue 3, Page e100-e104, March 2026.
Summary A 9‐year‐old male castrated Standardbred was presented for evaluation of a comminuted right front first phalanx fracture. On initial clinical examination, mild haemoconcentration and increased vital parameters were noted. After overnight hospitalisation, the horse underwent general anaesthesia for surgical fracture repair.
I. Lutvikadic, K. Hopster, B. Driessen
wiley   +1 more source