Results 161 to 170 of about 16,876 (211)

Pregnane X Receptor in Drug Development

, 2011
Ong, Su Sien, Wang, Yue-Ming, Chai, Sergio C., Chen, Taosheng   +3 more
openaire   +3 more sources

Activation of pregnane X receptor protects against cholestatic liver injury by inhibiting hepatocyte pyroptosis. [PDF]

Acta Pharmacol Sin
Liang HF, Yang X, Li HL, Li X, Tian JN, Su HG, Huang M, Fang JH, Bi HC.   +8 more
europepmc   +1 more source

Activation of pregnane X receptor sensitizes alcoholic steatohepatitis by transactivating fatty acid binding protein 4. [PDF]

Acta Pharm Sin B
Zhang Y, Hu B, Guan S, Li P, Guo Y, Xu P, Niu Y, Li Y, Feng Y, Du J, Xu J, Guan X, Gu J, Sun H, Huang M.   +14 more
europepmc   +1 more source

Pregnenolone 16-Alpha Carbonitrile, an Agonist of Rodent Pregnane X Receptor, Regulates Testosterone Biosynthesis in Rodent Leydig Cells. [PDF]

J Xenobiot
Salamat JM, Ayala EM, Huang CJ, Wilbanks FS, Knight RC, Akingbemi BT, Pondugula SR.   +6 more
europepmc   +1 more source

Pregnane X Receptor Activation in Liver Macrophages Protects against Endotoxin-Induced Liver Injury. [PDF]

Adv Sci (Weinh)
Zhao T, Zhong G, Wang Y, Cao R, Song S, Li Y, Wan G, Sun H, Huang M, Bi H, Jiang Y.   +10 more
europepmc   +1 more source

A Combined Approach for Rapid Dereplication of Herb-Drug Interaction Causative Agents in Botanical Extracts-A Molecular Networking Strategy To Identify Potential Pregnane X Receptor (PXR) Modulators in Yohimbe. [PDF]

ACS Omega
Annam SCVAR, Neal WM, Pandey P, Avula B, Katragunta K, Husain I, Khan SI, Koturbash I, Gurley BJ, Khan IA, Chittiboyina AG.   +10 more
europepmc   +1 more source

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor.

PLoS ONE, 2014
doaj   +3 more sources

Pregnane X Receptor Signaling Pathway and Vitamin K: Molecular Mechanisms and Clinical Relevance in Human Health. [PDF]

Cells
Staudinger JL, Mahroke A, Patel G, Dattel C, Reddy S.   +4 more
europepmc   +1 more source

Computationally-Assisted Discovery and Assignment of a New Class of 6/6/5/5 Fused-Ring Diterpene Acting as Pregnane X Receptor Ligands from <i>Isodon serra</i>. [PDF]

J Nat Prod
Bian Z, Liu X, Hu S, Li H, Wood JS, Williamson RT, Liu J, Chen Y, Shi J, Cummins CL, Ferreira D, Choo YM, Wang S, Hamann MT, Wang X.   +14 more
europepmc   +1 more source

Pregnane X receptor knockout mitigates weight gain and hepatic metabolic dysregulation in female C57BL/6 J mice on a long-term high-fat diet. [PDF]

Biomed Pharmacother
Gebreyesus LH, Choi S, Neequaye P, Mahmoud M, Mahmoud M, Ofosu-Boateng M, Twum E, Nnamani DO, Wang L, Yadak N, Ghosh S, Gonzalez FJ, Gyamfi MA.   +12 more
europepmc   +1 more source