Results 161 to 170 of about 18,065 (250)

Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis. [PDF]

Front Pharmacol
Rao S, Mei Y, Shi L, Li H, Zhou M, Meng Z, Zhao Z, Li S, Sun W, Tian Q.   +9 more
europepmc   +1 more source

Correction: Structural and Functional Similarity of Amphibian Constitutive Androstane Receptor with Mammalian Pregnane X Receptor. [PDF]

PLoS ONE, 2016
Marianne Mathäs, Christian Nusshag, Oliver Burk, Ute Gödtel-Armbrust, Holger Herlyn, Leszek Wojnowski, Björn Windshügel   +6 more
doaj   +1 more source

Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions. [PDF]

Nat Commun, 2023
Fan S, Yan Y, Xia Y, Zhou Z, Luo L, Zhu M, Han Y, Yao D, Zhang L, Fang M, Peng L, Yu J, Liu Y, Gao X, Guan H, Li H, Wang C, Wu X, Zhu H, Cao Y, Huang C.   +20 more
europepmc   +1 more source

Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression

Takumi Sato, Ryota Shizu, Ryonosuke Baba, Akira Ooka, Takuomi Hosaka, Yuichiro Kanno, Kouichi Yoshinari   +6 more
openalex   +1 more source

Pregnane X receptor protects against age-related bone loss in males via PI3K/Akt-mediated inhibition of apoptosis. [PDF]

Cell Death Discov
Li S, Xu Y, Xu W, Zhang D, Lin X, Hu P, Si H.   +6 more
europepmc   +1 more source

Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam [PDF]

, 2018
Akk, Gustav, Cao, Lily Q, Chakrabarti, Shampuma, Evers, Alex S, Germann, Allison L, Mennerick, Steven, Montana, Michael C, Shin, Daniel J, Wozniak, David F, Yuede, Carla M   +9 more
core   +1 more source

Expression and Prognostic Implication of the Nuclear Receptors Farnesoid X Receptor and Pregnane X Receptor in Human Cholangiocarcinoma. [PDF]

Cancer Diagn Progn
Sa-Ngiamwibool P, Yoshinari K, Shizu R, Kongpetch S, Prawan A, Senggunprai L.   +5 more
europepmc   +1 more source

Hepatic ZBTB22-mediated detoxification ameliorates acetaminophen-induced liver injury by inhibiting pregnane X receptor signaling. [PDF]

iScience, 2023
Chen Y, Cui T, Xiao S, Li T, Zhong Y, Tang K, Guo J, Huang S, Chen J, Li J, Wang Q, Huang J, Pan H, Gao Y.   +13 more
europepmc   +1 more source

Identification and characterization of phosphorylation sites within the pregnane X receptor protein

, 2013
Ayesha Elias, Anthony A. High, Ashutosh Mishra, Su Sien Ong, Jing Wu, Junmin Peng, Taosheng Chen   +6 more
openalex   +1 more source

Pregnane X receptor activation alleviates renal fibrosis in mice via interacting with p53 and inhibiting the Wnt7a/β-catenin signaling. [PDF]

Acta Pharmacol Sin, 2023
Ming WH, Luan ZL, Yao Y, Liu HC, Hu SY, Du CX, Zhang C, Zhao YH, Huang YZ, Sun XW, Qiao RF, Xu H, Guan YF, Zhang XY.   +13 more
europepmc   +1 more source