Results 151 to 160 of about 8,350 (160)

High-Throughput Evaluation Method for Drug Association with Pregnane X Receptor (PXR) Using Differential Scanning Fluorometry

SLAS Discovery, 2013
Mitsuhiro Sekiguchi, Yoshihiro Kobashigawa, Toshio Teramura   +2 more
exaly  

Development of in silico filters to predict activation of the pregnane X receptor (PXR) by structurally diverse drug-like molecules

Bioorganic and Medicinal Chemistry, 2012
Hans Matter, Lennart T Anger, Stefan Güssregen   +2 more
exaly  

Synthetic Drugs and Natural Products as Modulators of Constitutive Androstane Receptor (Car) and Pregnane X Receptor (PXR)

Drug Metabolism Reviews, 2006
Thomas K H Chang, David J Waxman
exaly  

Identification of polymorphisms in the 3′-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism

Xenobiotica, 2010
Lisa L Von Moltke, David J Greenblatt
exaly  

Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR)

Bioorganic and Medicinal Chemistry Letters, 2008
Bhaskar C Das, Sean Kim, Michael Sinz
exaly  

Correlation of High-Throughput Pregnane X Receptor (PXR) Transactivation and Binding Assays

Journal of Biomolecular Screening, 2004
Sean Kim, Taosheng Chen, Dianlin Xie
exaly  

Pregnane X receptor (PXR) – a contributor to the diabetes epidemic?

Drug Metabolism and Drug Interactions, 2014
Janne Hukkanen, Jukka Hakkola, Jaana Rysa   +2 more
exaly  

Attenuating pregnane X receptor (PXR) activation: A molecular modelling approach

Xenobiotica, 2007
exaly  

Activation of Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) by Herbal Medicines

AAPS Journal, 2009
Thomas K H Chang, Chang Thomas K H
exaly  

The pregnane X receptor: from bench to bedside

Expert Opinion on Drug Metabolism and Toxicology, 2008
Jeffrey R Idle, Frank J Gonzalez
exaly