Results 1 to 10 of about 13,268 (174)

Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis. [PDF]

Front Pharmacol
Rao S, Mei Y, Shi L, Li H, Zhou M, Meng Z, Zhao Z, Li S, Sun W, Tian Q.   +9 more
europepmc   +1 more source

Recent advances in gut microbiota metabolite regulation of hepatic pregnane X receptor. [PDF]

Front Immunol
Lin T, Chen Y, Liu L, Wu T, Qian Y, Jin B.   +5 more
europepmc   +1 more source

Hypertension in Overweight and Obesity: Sex-Specific Role of 4β-Hydroxycholesterol. [PDF]

J Am Heart Assoc
Rahunen R, Merikallio H, Rinne V, Savolainen MJ, Hukkanen J.   +4 more
europepmc   +1 more source

Bile acid signaling mediates gut microbiota regulation of host lipid metabolism. [PDF]

Front Microbiol
Liu M, He C, Lv X, Zheng W, Yin J, Li Y, Ma J.   +6 more
europepmc   +1 more source

PROTAC repurposing uncovers a noncanonical binding surface that mediates chemical degradation of nuclear receptors. [PDF]

Nat Commun
Huber AD, Lin W, Jung YH, Poudel S, Yang G, Wu J, Carrigan AG, Pagala V, Wang W, Fu Y, Yuan ZF, Byrum SD, Yang K, Gee RRF, Arnold ED, Loughran AJ, Wang J, Pruett-Miller SM, Peng J, Chen T.   +19 more
europepmc   +1 more source

From Genotype to Functional Risk: A Multi-Omic Approach to Predicting Thiopurine and Methotrexate Co-Therapy-Induced Liver Injury. [PDF]

Pharmaceuticals (Basel)
Molnár D, Reznik E, Porrogi P.
europepmc   +1 more source

Role and progression of bile acid metabolism in mediating Th17/Treg homeostasis in inflammatory bowel disease. [PDF]

iScience
Yue S, Tan Y, Gong L, Liao F.
europepmc   +1 more source

Malignant hypertension and pseudohyperaldosteronism associated with rifampicin therapy. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Szedleski A, Ilbert C, Goncette V, Vroonen L, Huart J.   +4 more
europepmc   +1 more source

Berberine and berberrubine promote the expression of CYP3A4 via enhancing the binding of nuclear receptor PXR. [PDF]

BMC Pharmacol Toxicol
Xiao GM, Lu T, Zhu D, Liu MY.
europepmc   +1 more source