Results 141 to 150 of about 8,350 (160)

Molecular Signature of Cisplatin Resistance in Ovarian Cancer Identifies Therapeutic Opportunities for Re-sensitization. [PDF]

J Cancer
Mansour M, van Ginkel S, Alata M, Bani I, Elhussin I.   +4 more
europepmc   +1 more source

Expression and Prognostic Implication of the Nuclear Receptors Farnesoid X Receptor and Pregnane X Receptor in Human Cholangiocarcinoma. [PDF]

Cancer Diagn Progn
Sa-Ngiamwibool P, Yoshinari K, Shizu R, Kongpetch S, Prawan A, Senggunprai L.   +5 more
europepmc   +1 more source

Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis. [PDF]

Front Pharmacol
Rao S, Mei Y, Shi L, Li H, Zhou M, Meng Z, Zhao Z, Li S, Sun W, Tian Q.   +9 more
europepmc   +1 more source

Hypomethylation of the PXR gene promoter drives its overexpression in cisplatin-resistant EOC. [PDF]

Discov Oncol
Wang J, Zhou JY, Chen ZC, Cheng M, Hu YC, Han Q.   +5 more
europepmc   +1 more source

Patchouli alcohol suppresses <i>Helicobacter pylori</i>-associated gastric cancer by activating PXR to inhibit the Wnt/β-catenin pathway and EMT. [PDF]

Front Pharmacol
Zhang X, Zeng Q, Guo P, Xu Y, Ma R, Li J.   +5 more
europepmc   +1 more source

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Cytochrome P450 Gene Regulation: Reporter Assays to Assess Pregnane X Receptor (PXR, NR1I2) Activation

Methods in Pharmacology and Toxicology, 2021
Judy L Raucy
exaly  

Pregnane X receptor (PXR) protects against cisplatin-induced acute kidney injury in mice

Biochimica Et Biophysica Acta - Molecular Basis of Disease, 2021
Cong Zhang, Wenhua Ming, Chunxiu Du
exaly  

Target Hopping from Protein Kinases to PXR: Identification of Small-Molecule Protein Kinase Inhibitors as Selective Modulators of Pregnane X Receptor from TüKIC Library

Cells, 2022
Tatu Pantsar, Azam Rashidian, Matthias Schwab   +2 more
exaly  

Pregnane X receptor (PXR) represses osteoblast differentiation through repression of the Hedgehog signaling pathway

Experimental Cell Research, 2022
Shousaku Itoh, Toshihiro Inubushi, Chizuko Inui-Yamamoto   +2 more
exaly