Differential gene regulation by SR12813 and rifampicin: Insights into PXR and PPARγ activation and metabolic pathway modulation in LS180 colon cancer cells. [PDF]
Brobst D +13 more
europepmc +1 more source
Pregnane X Receptor Regulates Human Endocrine System by Inducing Sex Hormone-Binding Globulin Expression. [PDF]
Ahonen MH +5 more
europepmc +1 more source
Dexamethasone-Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH-7 Cells. [PDF]
Yu H, Lee SH, Kim JH, Kim SJ, Kang HE.
europepmc +1 more source
The novel third-generation antipsychotic drug brexpiprazole affects hepatic transcription factors, serum hormone levels, and cytochrome P450 enzymes after prolonged treatment: pharmacological significance. [PDF]
Danek PJ, Pukło R, Daniel WA.
europepmc +1 more source
TNFAIP1 suppresses hepatocellular carcinoma progression via the PXR/CYP3A4 signaling axis. [PDF]
Nie Q +5 more
europepmc +1 more source
Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction-associated steatohepatitis in mice. [PDF]
Basaly V +12 more
europepmc +1 more source
In Silico Comparison of Rifampicin and 25-desacetyl Rifampicin-Induced PXR-Mediated CYP450 Transcriptional Response in 3D Primary Human Hepatocytes. [PDF]
Kahiya ET +5 more
europepmc +1 more source
Coenzyme Q10 protects against atorvastatin-induced hepatotoxicity via attenuation of oxidative stress and functional modulation of CYP3A1. [PDF]
Abdel-Rasol MA +4 more
europepmc +1 more source
Metabolic Disruption and Steatosis Induced by Drinking Water Disinfection Byproducts in HepG2 and HUH7 Cells. [PDF]
Mollari M +9 more
europepmc +1 more source

