Results 51 to 60 of about 6,716 (130)

Bioinformatic research of the gene "pregnane X receptor" (PXR) homologues in marine invertebrates

, 2018
The xenobiotic detoxification enzymes are regulated, in mammals and other animals, by a specific group of nuclear receptors. In particular pregnane X receptor (PXR) has shown incredible versatility in recognizing a broad range of xenobiotics and natural compounds which function as agonists of the protein.
Ribeiro, Daniel, Martins, José C., Campos, Alexandre   +2 more
openaire   +1 more source

Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXRα) and Pregnane X Receptor (PXR). [PDF]

Evid Based Complement Alternat Med, 2019
Tai TS, Tien N, Shen HY, Chu FY, Wang CCN, Lu CH, Yu HI, Kung FP, Chuang HH, Lee YR, Chang HY, Lim YP.   +11 more
europepmc   +1 more source

Pregnane X receptor (PXR) as a prognostic marker and therapeutic target in kidney renal clear cell carcinoma (KIRC) via AMPK pathway regulation. [PDF]

Sci Rep
Hu WJ, Liu M, Bao YN, Su BW, Sui X, Cui XH, Wang GY, Wen L, Wen RK, Wang WH, Yang HX, Luan ZL.   +11 more
europepmc   +1 more source

Probing Ligand Structure-Activity Relationships in Pregnane X Receptor (PXR): Efavirenz and 8-Hydroxyefavirenz Exhibit Divergence in Activation. [PDF]

ChemMedChem, 2018
Narayanan B, Lade JM, Heck CJS, Dietz KD, Wade H, Bumpus NN.   +5 more
europepmc   +1 more source

A Combined Approach for Rapid Dereplication of Herb-Drug Interaction Causative Agents in Botanical Extracts-A Molecular Networking Strategy To Identify Potential Pregnane X Receptor (PXR) Modulators in Yohimbe. [PDF]

ACS Omega
Annam SCVAR, Neal WM, Pandey P, Avula B, Katragunta K, Husain I, Khan SI, Koturbash I, Gurley BJ, Khan IA, Chittiboyina AG.   +10 more
europepmc   +1 more source

Rifaximin, a pregnane X receptor (PXR) activator regulates apoptosis in a murine model of breast cancer. [PDF]

RSC Adv, 2018
Gautam S, Singh P, Singh M, Roy S, Rawat JK, Yadav RK, Devi U, Gupta PS, Saraf SA, Kaithwas G.   +9 more
europepmc   +1 more source

The pregnane X receptor (PXR) and the nuclear receptor corepressor 2 (NCoR2) modulate cell growth in head and neck squamous cell carcinoma. [PDF]

PLoS One, 2018
Rigalli JP, Reichel M, Reuter T, Tocchetti GN, Dyckhoff G, Herold-Mende C, Theile D, Weiss J.   +7 more
europepmc   +1 more source

Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation. [PDF]

PLoS One, 2016
Pinne M, Ponce E, Raucy JL.
europepmc   +1 more source

Malignant hypertension and pseudohyperaldosteronism associated with rifampicin therapy. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Szedleski A, Ilbert C, Goncette V, Vroonen L, Huart J.   +4 more
europepmc   +1 more source

Recent advances in gut microbiota metabolite regulation of hepatic pregnane X receptor. [PDF]

Front Immunol
Lin T, Chen Y, Liu L, Wu T, Qian Y, Jin B.   +5 more
europepmc   +1 more source